CONTENTS/ABSTRACTS

 PDFs of all articles are available from IOS Press. 

F O R   A U T H O R S

VOLUMES 1-6

VOLUME 7

VOLUME 8

VOLUME 9

VOLUME 10

VOLUME 11

VOLUME 12

VOLUME 13

VOLUME 14

VOLUME 15

Volume 4, Number 3, June 2002: Guest Editor, Craig S. Atwood
Special Issue: Challenging Views of Alzheimer Disease
 

Pages 129-130

Forward: Challenging Views of Alzheimer’s Disease
Organizers: Keith A. Crutcher, Stephen R. Robinson, and Mark A. Smith

 
• Debate 1: Does Amyloid or its Precursor Cause Familial AD? (Moderator: Stephen Synder)
   
  Pages 133-138
  • Steve Estus, David Borchelt, Mark S. Kindy, Robert Vassar
    Aß deposition is essential to AD neuropathology

• Debate 2: ApoE4: Is it the Absence of Good of the Presence of Bad? (Moderator: J. Wesson Ashford)
   
  Pages 141-143
  • J. Wesson Asford
    ApoE4: Is it the Absence of Good or the Presence of Bad?

Pages 145-154
• G. William Rebeck, Mark Kindy, Mary Jo LaDu
  Apolipoprotein E and Alzheimer’s disease: the protective effects of ApoE2 and E3
 
Pages 155-163
• Bruce Teter, Jacob Raber, Britto Nathan, Keith A. Crutcher
  The presence of apoE4, not the absence of apoE3, contributes to AD pathology

• Debate 3: Is Non-Familial AD Inherited? (Moderator: Robert Petersen)

Pages 167-168
• Robert B. Petersen
  You can take the genome out of the organism, but can you take the organism out of the environment?

Pages 169-177
• J. Wesson Ashford, James A. Mortimer
  Non-familial Alzheimer’s disease is mainly due to genetic factors
 
Pages 179-189
• William B. Grant, Arezoo Campbell, Ruth F. Itzhaki, John Savory
  The significance of environmental factors in the etiology of Alzheimer’s disease

• Debate 4: Fire! Are Oxidation and Inflammation the Culprits in AD? (Moderator: Hossein Ghanbari)

Pages 193-201
• D. Allan Butterfield, Sue Griffin, Gerald Münch, Giulio Maria Pasinetti
  Amyloid ß-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer’s disease brain exists

Pages 203-214
• Craig S. Atwood, Stephen R. Robinson, and Mark A. Smith
  Amyloid-ß: redox-metal chelator and antioxidant

• Debate 5: Is AD a Vascular or a Metabolic Disorder? (Moderator: Creighton "Tony" Phelps)

Pages 217-223
• P Grammas, M Yamada, B Zlokovic
  The cerebromicrovasculature: a key player in the pathogenesis of AD

  Pages 225-232

• John P Blass, Gary E Gibson, Siegfried Hoyer
  The role of the metabolic lesion in Alzheimer’s disease

• Debate 6: Were the Tauists Right All Along? (Moderator: David Morgan)

Pages 235-238
• Khalid Iqbal, Inge Grundke-Iqbal
  Neurofibrillary pathology leads to synaptic loss and not the other way around in Alzheimer disease

• Debate 7: Cyclin Towards, or Away From, Dementia? (Moderator: John Blass)

Pages 241-242
• John P. Blass
  Debate 7: Cyclin Towards, or Away From, Dementia?

Pages 243-247
• Karl Herrup, Thomas Arendt
  Re-expression of cell cycle proteins induces neuronal cell death during Alzheimer's disease

  Pages 249-254

• Robert Bowser, Mark A. Smith
  Cell cycle proteins in Alzheimer’s disease:  plenty of wheels but no cycle

• Debate 8: Promising New Directions for Drugs and Diagnostics? (Moderator: Chris Kircher)
   
  Pages 257-260
  • Dave Morgan and R. Kennedy Keller
    What evidence would prove the amyloid hypothesis? Towards rational drug treatments for Alzheimer's disease

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