%0 Journal Article %J J Alzheimers Dis %D 2020 %T Death Rate Due to COVID-19 in Alzheimer's Disease and Frontotemporal Dementia. %A Matías-Guiu, Jordi A %A Pytel, Vanesa %A Matías-Guiu, Jorge %K Age Factors %K Aged %K Aged, 80 and over %K Alzheimer Disease %K Coronavirus Infections %K COVID-19 %K Female %K Frontotemporal Dementia %K Humans %K Hypertension %K Independent Living %K Male %K Nursing Homes %K Pandemics %K Pneumonia, Viral %K Prevalence %K Risk Factors %X

We aimed to evaluate the frequency and mortality of COVID-19 in patients with Alzheimer's disease (AD) and frontotemporal dementia (FTD). We conducted an observational case series. We enrolled 204 patients, 15.2% of whom were diagnosed with COVID-19, and 41.9% of patients with the infection died. Patients with AD were older than patients with FTD (80.36±8.77 versus 72.00±8.35 years old) and had a higher prevalence of arterial hypertension (55.8% versus 26.3%). COVID-19 occurred in 7.3% of patients living at home, but 72.0% of those living at care homes. Living in care facilities and diagnosis of AD were independently associated with a higher probability of death. We found that living in care homes is the most relevant factor for an increased risk of COVID-19 infection and death, with AD patients exhibiting a higher risk than those with FTD.

%B J Alzheimers Dis %V 78 %P 537-541 %8 2020 %G eng %N 2 %1 https://www.ncbi.nlm.nih.gov/pubmed/33074240?dopt=Abstract %R 10.3233/JAD-200940