%0 Journal Article %J J Alzheimers Dis %D 2016 %T Higher Fasting Plasma Glucose Levels, within the Normal Range, are Associated with Decreased Processing Speed in High Functioning Young Elderly. %A Raizes, Meytal %A Elkana, Odelia %A Franko, Motty %A Ravona Springer, Ramit %A Segev, Shlomo %A Beeri, Michal Schnaider %K Aged %K Blood Glucose %K Cognition %K Diabetes Mellitus, Type 2 %K Fasting %K Female %K Humans %K Linear Models %K Male %K Middle Aged %K Neuropsychological Tests %K Psychomotor Performance %K Reaction Time %K Reference Values %X

We explored the association of plasma glucose levels within the normal range with processing speed in high functioning young elderly, free of type 2 diabetes mellitus (T2DM). A sample of 41 participants (mean age = 64.7, SD = 10; glucose 94.5 mg/dL, SD = 9.3), were examined with a computerized cognitive battery. Hierarchical linear regression analysis showed that higher plasma glucose levels, albeit within the normal range (<110 mg/dL), were associated with longer reaction times (p <  0.01). These findings suggest that even in the subclinical range and in the absence of T2DM, monitoring plasma glucose levels may have an impact on cognitive function.

%B J Alzheimers Dis %V 49 %P 589-92 %8 2016 %G eng %N 3 %1 http://www.ncbi.nlm.nih.gov/pubmed/26484908?dopt=Abstract %R 10.3233/JAD-150433