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Amyloid beta-Peptides
J. C. Morris, Roe, C. M., Xiong, C., Fagan, A. M., Goate, A. M., Holtzman, D. M., and Mintun, M. A., APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging., Ann Neurol, vol. 67, no. 1, pp. 122-31, 2010.
D. Head, Bugg, J. M., Goate, A. M., Fagan, A. M., Mintun, M. A., Benzinger, T., Holtzman, D. M., and Morris, J. C., Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition., Arch Neurol, vol. 69, no. 5, pp. 636-43, 2012.
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M., Human apoE isoforms differentially regulate brain amyloid-β peptide clearance., Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
A. W. Bero, Yan, P., Roh, J. Hoon, Cirrito, J. R., Stewart, F. R., Raichle, M. E., Lee, J. - M., and Holtzman, D. M., Neuronal activity regulates the regional vulnerability to amyloid-β deposition., Nat Neurosci, vol. 14, no. 6, pp. 750-6, 2011.
S. Simonovitch, Schmukler, E., Bespalko, A., Iram, T., Frenkel, D., Holtzman, D. M., Masliah, E., Michaelson, D. M., and Pinkas-Kramarski, R., Impaired Autophagy in APOE4 Astrocytes., J Alzheimers Dis, vol. 51, no. 3, pp. 915-27, 2016.

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