Biblio

Export 20 results:
Author Title Type [ Year(Asc)]
Filters: Keyword is Dose-Response Relationship, Drug  [Clear All Filters]
2022
X. Hua, Church, K., Walker, W., L'Hostis, P., Viardot, G., Danjou, P., Hendrix, S., and Moebius, H. J., “Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Positive Modulator of HGF/MET, Fosgonimeton, in Healthy Volunteers and Subjects with Alzheimer's Disease: Randomized, Placebo-Controlled, Double-Blind, Phase I Clinical Trial.”, J Alzheimers Dis, vol. 86, no. 3, pp. 1399-1413, 2022.
2017
D. E. Moss, Perez, R. G., and Kobayashi, H., “Cholinesterase Inhibitor Therapy in Alzheimer's Disease: The Limits and Tolerability of Irreversible CNS-Selective Acetylcholinesterase Inhibition in Primates.”, J Alzheimers Dis, vol. 55, no. 3, pp. 1285-1294, 2017.
M. Romeo, Stravalaci, M., Beeg, M., Rossi, A., Fiordaliso, F., Corbelli, A., Salmona, M., Gobbi, M., Cagnotto, A., and Diomede, L., “Humanin Specifically Interacts with Amyloid-β Oligomers and Counteracts Their in vivo Toxicity.”, J Alzheimers Dis, vol. 57, no. 3, pp. 857-871, 2017.
G. Marwarha, Rostad, S., Lilek, J., Kleinjan, M., Schommer, J., and Ghribi, O., “Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.”, J Alzheimers Dis, vol. 57, no. 3, pp. 907-925, 2017.
L. - S. Liu, Bai, X. - Q., Gao, Y., Wu, Q., Ren, Z., Li, Q., Pan, L. - H., He, N. - Y., Peng, J., and Tang, Z. - H., “PCSK9 Promotes oxLDL-Induced PC12 Cell Apoptosis Through the Bcl-2/Bax-Caspase 9/3 Signaling Pathway.”, J Alzheimers Dis, vol. 57, no. 3, pp. 723-734, 2017.
2016
A. Belkacemi and Ramassamy, C., “Anthocyanins Protect SK-N-SH Cells Against Acrolein-Induced Toxicity by Preserving the Cellular Redox State.”, J Alzheimers Dis, vol. 50, no. 4, pp. 981-98, 2016.
S. Eketjäll, Janson, J., Kaspersson, K., Bogstedt, A., Jeppsson, F., Fälting, J., Haeberlein, S. Budd, Kugler, A. R., Alexander, R. C., and Cebers, G., “AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics.”, J Alzheimers Dis, vol. 50, no. 4, pp. 1109-23, 2016.
Z. - Q. Xu, Huang, H., Chen, Y. - L., Gao, Y. - Y., Xu, J., Marshall, C., Cai, Z. - Y., and Xiao, M., “Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis.”, J Alzheimers Dis, vol. 51, no. 1, pp. 179-95, 2016.
H. Jin, Chen, T., Li, G., Wang, C., Zhang, B., Cao, X., Sha, S., Wan, Q., and Chen, L., “Dose-Dependent Neuroprotection and Neurotoxicity of Simvastatin through Reduction of Farnesyl Pyrophosphate in Mice Treated with Intracerebroventricular Injection of Aβ 1-42.”, J Alzheimers Dis, vol. 50, no. 2, pp. 501-16, 2016.
A. M. Masoud, Bihaqi, S. W., Machan, J. T., Zawia, N. H., and Renehan, W. E., “Early-Life Exposure to Lead (Pb) Alters the Expression of microRNA that Target Proteins Associated with Alzheimer's Disease.”, J Alzheimers Dis, vol. 51, no. 4, pp. 1257-64, 2016.
T. Porter, Bharadwaj, P., Groth, D., Paxman, A., Laws, S. M., Martins, R. N., and Verdile, G., “The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity.”, J Alzheimers Dis, vol. 50, no. 3, pp. 895-905, 2016.
H. Florian, Meier, A., Gauthier, S., Lipschitz, S., Lin, Y., Tang, Q., Othman, A. A., Robieson, W. Z., and Gault, L. M., “Efficacy and Safety of ABT-126 in Subjects with Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors: A Randomized, Double-Blind, Placebo-Controlled Study.”, J Alzheimers Dis, vol. 51, no. 4, pp. 1237-47, 2016.
D. Chu, Tan, J., Xie, S., Jin, N., Yin, X., Gong, C. - X., Iqbal, K., and Liu, F., “GSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner.”, J Alzheimers Dis, vol. 49, no. 2, pp. 365-75, 2016.
M. Díaz, Fabelo, N., Casañas-Sánchez, V., Marin, R., Gómez, T., Quinto-Alemany, D., and Pérez, J. A., “Hippocampal Lipid Homeostasis in APP/PS1 Mice is Modulated by a Complex Interplay Between Dietary DHA and Estrogens: Relevance for Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 2, pp. 459-81, 2016.
M. Zhu, Huang, C., Ma, X., Wu, R., Zhu, W., Li, X., Liang, Z., Deng, F., Zhu, J., Xie, W., Yang, X., Jiang, Y., Wang, S., Wu, J., Geng, S., Xie, C., and Zhong, C., “Modulation of miR-19 in Aluminum-Induced Neural Cell Apoptosis.”, J Alzheimers Dis, vol. 50, no. 4, pp. 1149-62, 2016.
M. Fà, Zhang, H., Staniszewski, A., Saeed, F., Shen, L. W., Schiefer, I. T., Siklos, M. I., Tapadar, S., Litosh, V. A., Libien, J., Petukhov, P. A., Teich, A. F., Thatcher, G. R. J., and Arancio, O., “Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 3, pp. 707-21, 2016.
S. Lim, Choi, J. Gyu, Moon, M., Kim, H. Geun, Lee, W., Bak, H. - R., Sung, H., Park, C. Hye, Kim, S. Yeou, and Oh, M. Sook, “An Optimized Combination of Ginger and Peony Root Effectively Inhibits Amyloid-β Accumulation and Amyloid-β-Mediated Pathology in AβPP/PS1 Double-Transgenic Mice.”, J Alzheimers Dis, vol. 50, no. 1, pp. 189-200, 2016.
M. Tong, Deochand, C., Didsbury, J., and de la Monte, S. M., “T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.”, J Alzheimers Dis, vol. 51, no. 1, pp. 123-38, 2016.
F. Pasquier, Sadowsky, C., Holstein, A., Leterme, G. Le Prince, Peng, Y., Jackson, N., Fox, N. C., Ketter, N., Liu, E., and J Ryan, M., “Two Phase 2 Multiple Ascending-Dose Studies of Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Mild-to-Moderate Alzheimer's Disease.”, J Alzheimers Dis, vol. 51, no. 4, pp. 1131-43, 2016.
M. Xie, Han, Y., Yu, Q., Wang, X., Wang, S., and Liao, X., “UCH-L1 Inhibition Decreases the Microtubule-Binding Function of Tau Protein.”, J Alzheimers Dis, vol. 49, no. 2, pp. 353-63, 2016.