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Hippocampus
A. de Calignon, Polydoro, M., Suárez-Calvet, M., William, C., Adamowicz, D. H., Kopeikina, K. J., Pitstick, R., Sahara, N., Ashe, K. H., Carlson, G. A., Spires-Jones, T. L., and Hyman, B. T., Propagation of tau pathology in a model of early Alzheimer's disease., Neuron, vol. 73, no. 4, pp. 685-97, 2012.
M. Jin, Shepardson, N., Yang, T., Chen, G., Walsh, D., and Selkoe, D. J., Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration., Proc Natl Acad Sci U S A, vol. 108, no. 14, pp. 5819-24, 2011.
M. Bolós, Llorens-Martín, M., Jurado-Arjona, J., Hernández, F., Rábano, A., and Avila, J., Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo., J Alzheimers Dis, vol. 50, no. 1, pp. 77-87, 2016.
S. A. Villeda, Plambeck, K. E., Middeldorp, J., Castellano, J. M., Mosher, K. I., Luo, J., Smith, L. K., Bieri, G., Lin, K., Berdnik, D., Wabl, R., Udeochu, J., Wheatley, E. G., Zou, B., Simmons, D. A., Xie, X. S., Longo, F. M., and Wyss-Coray, T., Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice., Nat Med, vol. 20, no. 6, pp. 659-63, 2014.
A. Bakker, Krauss, G. L., Albert, M. S., Speck, C. L., Jones, L. R., Stark, C. E., Yassa, M. A., Bassett, S. S., Shelton, A. L., and Gallagher, M., Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment., Neuron, vol. 74, no. 3, pp. 467-74, 2012.
K. Talbot, Wang, H. - Y., Kazi, H., Han, L. - Y., Bakshi, K. P., Stucky, A., Fuino, R. L., Kawaguchi, K. R., Samoyedny, A. J., Wilson, R. S., Arvanitakis, Z., Schneider, J. A., Wolf, B. A., Bennett, D. A., Trojanowski, J. Q., and Arnold, S. E., Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline., J Clin Invest, vol. 122, no. 4, pp. 1316-38, 2012.
J. Gräff, Rei, D., Guan, J. - S., Wang, W. - Y., Seo, J., Hennig, K. M., Nieland, T. J. F., Fass, D. M., Kao, P. F., Kahn, M., Su, S. C., Samiei, A., Joseph, N., Haggarty, S. J., Delalle, I., and Tsai, L. - H., An epigenetic blockade of cognitive functions in the neurodegenerating brain., Nature, vol. 483, no. 7388, pp. 222-6, 2012.
C. R. Jack, Vemuri, P., Wiste, H. J., Weigand, S. D., Aisen, P. S., Trojanowski, J. Q., Shaw, L. M., Bernstein, M. A., Petersen, R. C., Weiner, M. W., and Knopman, D. S., Evidence for ordering of Alzheimer disease biomarkers., Arch Neurol, vol. 68, no. 12, pp. 1526-35, 2011.
A. Suzuki, Stern, S. A., Bozdagi, O., Huntley, G. W., Walker, R. H., Magistretti, P. J., and Alberini, C. M., Astrocyte-neuron lactate transport is required for long-term memory formation., Cell, vol. 144, no. 5, pp. 810-23, 2011.
K. I. Erickson, Voss, M. W., Prakash, R. Shaurya, Basak, C., Szabo, A., Chaddock, L., Kim, J. S., Heo, S., Alves, H., White, S. M., Wojcicki, T. R., Mailey, E., Vieira, V. J., Martin, S. A., Pence, B. D., Woods, J. A., McAuley, E., and Kramer, A. F., Exercise training increases size of hippocampus and improves memory., Proc Natl Acad Sci U S A, vol. 108, no. 7, pp. 3017-22, 2011.
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R., Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment., J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
S. E. Leh, Kälin, A. M., Schroeder, C., Park, M. Tae M., M Chakravarty, M., Freund, P., Gietl, A. F., Riese, F., Kollias, S., Hock, C., and Michels, L., Volumetric and shape analysis of the thalamus and striatum in amnestic mild cognitive impairment., J Alzheimers Dis, vol. 49, no. 1, pp. 237-49, 2016.
J. - P. Coutu, Goldblatt, A., H Rosas, D., and Salat, D. H., White Matter Changes are Associated with Ventricular Expansion in Aging, Mild Cognitive Impairment, and Alzheimer's Disease., J Alzheimers Dis, vol. 49, no. 2, pp. 329-42, 2016.
B. G. Schreurs and D Sparks, L., Dietary high cholesterol and trace metals in the drinking water increase levels of ABCA1 in the rabbit hippocampus and temporal cortex., J Alzheimers Dis, vol. 49, no. 1, pp. 201-9, 2016.
J. Ahdidan, Raji, C. A., DeYoe, E. A., Mathis, J., Noe, K. Ø., Rimestad, J., Kjeldsen, T. K., Mosegaard, J., Becker, J. T., and Lopez, O., Quantitative Neuroimaging Software for Clinical Assessment of Hippocampal Volumes on MR Imaging., J Alzheimers Dis, vol. 49, no. 3, pp. 723-32, 2016.
M. Fà, Zhang, H., Staniszewski, A., Saeed, F., Shen, L. W., Schiefer, I. T., Siklos, M. I., Tapadar, S., Litosh, V. A., Libien, J., Petukhov, P. A., Teich, A. F., Thatcher, G. R. J., and Arancio, O., Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease., J Alzheimers Dis, vol. 49, no. 3, pp. 707-21, 2016.
A. F. N. Rosenberger, Hilhorst, R., Coart, E., Barrado, L. García, Naji, F., Rozemuller, A. J. M., van der Flier, W. M., Scheltens, P., Hoozemans, J. J. M., and van der Vies, S. M., Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology., J Alzheimers Dis, vol. 49, no. 4, pp. 927-43, 2016.
M. Díaz, Fabelo, N., Casañas-Sánchez, V., Marin, R., Gómez, T., Quinto-Alemany, D., and Pérez, J. A., Hippocampal Lipid Homeostasis in APP/PS1 Mice is Modulated by a Complex Interplay Between Dietary DHA and Estrogens: Relevance for Alzheimer's Disease., J Alzheimers Dis, vol. 49, no. 2, pp. 459-81, 2016.
J. Ku Chung, Plitman, E., Nakajima, S., M Chakravarty, M., Caravaggio, F., Takeuchi, H., Gerretsen, P., Iwata, Y., Patel, R., Mulsant, B. H., and Graff-Guerrero, A., Depressive Symptoms and Small Hippocampal Volume Accelerate the Progression to Dementia from Mild Cognitive Impairment., J Alzheimers Dis, vol. 49, no. 3, pp. 743-54, 2016.
I. W. M. van Uden, van der Holst, H. M., Tuladhar, A. M., van Norden, A. G. W., de Laat, K. F., Rutten-Jacobs, L. C. A., Norris, D. G., Claassen, J. A. H. R., van Dijk, E. J., Kessels, R. P. C., and de Leeuw, F. - E., White Matter and Hippocampal Volume Predict the Risk of Dementia in Patients with Cerebral Small Vessel Disease: The RUN DMC Study., J Alzheimers Dis, vol. 49, no. 3, pp. 863-73, 2016.
J. Liu, Zhang, X., Yu, C., Duan, Y., Zhuo, J., Cui, Y., Liu, B., Li, K., Jiang, T., and Liu, Y., Impaired Parahippocampus Connectivity in Mild Cognitive Impairment and Alzheimer's Disease., J Alzheimers Dis, vol. 49, no. 4, pp. 1051-64, 2016.
N. Bartolotti, Segura, L., and Lazarov, O., Diminished CRE-Induced Plasticity is Linked to Memory Deficits in Familial Alzheimer's Disease Mice., J Alzheimers Dis, vol. 50, no. 2, pp. 477-89, 2016.
G. Spalletta, Cravello, L., Gianni, W., Piras, F., Iorio, M., Cacciari, C., Casini, A. Rosa, Chiapponi, C., Sancesario, G., Fratangeli, C., Orfei, M. Donata, Caltagirone, C., and Piras, F., Homotaurine Effects on Hippocampal Volume Loss and Episodic Memory in Amnestic Mild Cognitive Impairment., J Alzheimers Dis, vol. 50, no. 3, pp. 807-16, 2016.
H. Jin, Chen, T., Li, G., Wang, C., Zhang, B., Cao, X., Sha, S., Wan, Q., and Chen, L., Dose-Dependent Neuroprotection and Neurotoxicity of Simvastatin through Reduction of Farnesyl Pyrophosphate in Mice Treated with Intracerebroventricular Injection of Aβ 1-42., J Alzheimers Dis, vol. 50, no. 2, pp. 501-16, 2016.
Z. - Q. Xu, Huang, H., Chen, Y. - L., Gao, Y. - Y., Xu, J., Marshall, C., Cai, Z. - Y., and Xiao, M., Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis., J Alzheimers Dis, vol. 51, no. 1, pp. 179-95, 2016.

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