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Mutation
K. R. LeVault, Tischkau, S. A., and Brewer, G. J., Circadian Disruption Reveals a Correlation of an Oxidative GSH/GSSG Redox Shift with Learning and Impaired Memory in an Alzheimer's Disease Mouse Model., J Alzheimers Dis, vol. 49, no. 2, pp. 301-16, 2016.
A. de Calignon, Polydoro, M., Suárez-Calvet, M., William, C., Adamowicz, D. H., Kopeikina, K. J., Pitstick, R., Sahara, N., Ashe, K. H., Carlson, G. A., Spires-Jones, T. L., and Hyman, B. T., Propagation of tau pathology in a model of early Alzheimer's disease., Neuron, vol. 73, no. 4, pp. 685-97, 2012.
R. Guerreiro, Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., Hazrati, L., Collinge, J., Pocock, J., Lashley, T., Williams, J., Lambert, J. - C., Amouyel, P., Goate, A., Rademakers, R., Morgan, K., Powell, J., St George-Hyslop, P., Singleton, A., and Hardy, J., TREM2 variants in Alzheimer's disease., N Engl J Med, vol. 368, no. 2, pp. 117-27, 2013.
A. Ezra, Rabinovich-Nikitin, I., Rabinovich-Toidman, P., and Solomon, B., Multifunctional Effect of Human Serum Albumin Reduces Alzheimer's Disease Related Pathologies in the 3xTg Mouse Model., J Alzheimers Dis, vol. 50, no. 1, pp. 175-88, 2016.
T. Jonsson, Atwal, J. K., Steinberg, S., Snaedal, J., Jonsson, P. V., Bjornsson, S., Stefansson, H., Sulem, P., Gudbjartsson, D., Maloney, J., Hoyte, K., Gustafson, A., Liu, Y., Lu, Y., Bhangale, T., Graham, R. R., Huttenlocher, J., Bjornsdottir, G., Andreassen, O. A., Jönsson, E. G., Palotie, A., Behrens, T. W., Magnusson, O. T., Kong, A., Thorsteinsdottir, U., Watts, R. J., and Stefansson, K., A mutation in APP protects against Alzheimer's disease and age-related cognitive decline., Nature, vol. 488, no. 7409, pp. 96-9, 2012.
Z. Rusznák, Kim, W. Scott, Hsiao, J. - H. T., Halliday, G. M., Paxinos, G., and Fu, Y. H., Early in vivo Effects of the Human Mutant Amyloid-β Protein Precursor (hAβPPSwInd) on the Mouse Olfactory Bulb., J Alzheimers Dis, vol. 49, no. 2, pp. 443-57, 2016.
M. Fà, Zhang, H., Staniszewski, A., Saeed, F., Shen, L. W., Schiefer, I. T., Siklos, M. I., Tapadar, S., Litosh, V. A., Libien, J., Petukhov, P. A., Teich, A. F., Thatcher, G. R. J., and Arancio, O., Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease., J Alzheimers Dis, vol. 49, no. 3, pp. 707-21, 2016.
P. Jul, Volbracht, C., de Jong, I. E. M., Helboe, L., Elvang, A. Brandt, and Pedersen, J. Torleif, Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model., J Alzheimers Dis, vol. 49, no. 3, pp. 783-95, 2016.
M. Díaz, Fabelo, N., Casañas-Sánchez, V., Marin, R., Gómez, T., Quinto-Alemany, D., and Pérez, J. A., Hippocampal Lipid Homeostasis in APP/PS1 Mice is Modulated by a Complex Interplay Between Dietary DHA and Estrogens: Relevance for Alzheimer's Disease., J Alzheimers Dis, vol. 49, no. 2, pp. 459-81, 2016.
S. Lim, Choi, J. Gyu, Moon, M., Kim, H. Geun, Lee, W., Bak, H. - R., Sung, H., Park, C. Hye, Kim, S. Yeou, and Oh, M. Sook, An Optimized Combination of Ginger and Peony Root Effectively Inhibits Amyloid-β Accumulation and Amyloid-β-Mediated Pathology in AβPP/PS1 Double-Transgenic Mice., J Alzheimers Dis, vol. 50, no. 1, pp. 189-200, 2016.
H. Qiu, Zhong, R., Liu, H., Zhang, F., Li, S., and Le, W., Chronic Sleep Deprivation Exacerbates Learning-Memory Disability and Alzheimer's Disease-Like Pathologies in AβPP(swe)/PS1(ΔE9) Mice., J Alzheimers Dis, vol. 50, no. 3, pp. 669-85, 2016.
A. E. Roher, Maarouf, C. L., and Kokjohn, T. A., Familial Presenilin Mutations and Sporadic Alzheimer's Disease Pathology: Is the Assumption of Biochemical Equivalence Justified?, J Alzheimers Dis, vol. 50, no. 3, pp. 645-58, 2016.
E. Premi, Cauda, F., Costa, T., Diano, M., Gazzina, S., Gualeni, V., Alberici, A., Archetti, S., Magoni, M., Gasparotti, R., Padovani, A., and Borroni, B., Looking for Neuroimaging Markers in Frontotemporal Lobar Degeneration Clinical Trials: A Multi-Voxel Pattern Analysis Study in Granulin Disease., J Alzheimers Dis, vol. 51, no. 1, pp. 249-62, 2016.
Z. - Q. Xu, Huang, H., Chen, Y. - L., Gao, Y. - Y., Xu, J., Marshall, C., Cai, Z. - Y., and Xiao, M., Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis., J Alzheimers Dis, vol. 51, no. 1, pp. 179-95, 2016.
H. Leinonen, Lipponen, A., Gurevicius, K., and Tanila, H., Normal Amplitude of Electroretinography and Visual Evoked Potential Responses in AβPP/PS1 Mice., J Alzheimers Dis, vol. 51, no. 1, pp. 21-6, 2016.
P. Chatterjee, Lim, W. L. F., Shui, G., Gupta, V. B., James, I., Fagan, A. M., Xiong, C., Sohrabi, H. R., Taddei, K., Brown, B. M., Benzinger, T., Masters, C., Snowden, S. G., Wenk, M. R., Bateman, R. J., Morris, J. C., and Martins, R. N., Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study., J Alzheimers Dis, vol. 50, no. 3, pp. 887-94, 2016.
J. - P. Morin, Cerón-Solano, G., Velázquez-Campos, G., Pacheco-López, G., Bermúdez-Rattoni, F., and Díaz-Cintra, S., Spatial Memory Impairment is Associated with Intraneural Amyloid-β Immunoreactivity and Dysfunctional Arc Expression in the Hippocampal-CA3 Region of a Transgenic Mouse Model of Alzheimer's Disease., J Alzheimers Dis, vol. 51, no. 1, pp. 69-79, 2016.
Y. Manso, Comes, G., López-Ramos, J. C., Belfiore, M., Molinero, A., Giralt, M., Carrasco, J., Adlard, P. A., Bush, A. I., Delgado-García, J. María, and Hidalgo, J., Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease., J Alzheimers Dis, vol. 51, no. 1, pp. 81-95, 2016.
G. Lou, Zhang, Q., Xiao, F., Xiang, Q., Su, Z., and Huang, Y., Intranasal TAT-haFGF Improves Cognition and Amyloid-β Pathology in an AβPP/PS1 Mouse Model of Alzheimer's Disease., J Alzheimers Dis, vol. 51, no. 4, pp. 985-90, 2016.
B. Ongali, Nicolakakis, N., Tong, X. - K., Aboulkassim, T., Imboden, H., and Hamel, E., Enalapril Alone or Co-Administered with Losartan Rescues Cerebrovascular Dysfunction, but not Mnemonic Deficits or Amyloidosis in a Mouse Model of Alzheimer's Disease., J Alzheimers Dis, vol. 51, no. 4, pp. 1183-95, 2016.
R. Sánchez-Valle, Monté, G. C., Sala-Llonch, R., Bosch, B., Fortea, J., Lladó, A., Antonell, A., Balasa, M., Bargalló, N., and Molinuevo, J. Luis, White Matter Abnormalities Track Disease Progression in PSEN1 Autosomal Dominant Alzheimer's Disease., J Alzheimers Dis, vol. 51, no. 3, pp. 827-35, 2016.
F. Guillot, Kemppainen, S., Lavasseur, G., Miettinen, P. O., Laroche, S., Tanila, H., and Davis, S., Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease., J Alzheimers Dis, vol. 51, no. 4, pp. 1157-73, 2016.
Y. Kim, Kim, C., Jang, H. Young, and Mook-Jung, I., Inhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation., J Alzheimers Dis, vol. 51, no. 4, pp. 1057-68, 2016.
S. Min Son, Shin, H. - J., Byun, J., Kook, S. Young, Moon, M., Chang, Y. Jin, and Mook-Jung, I., Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation., J Alzheimers Dis, vol. 51, no. 4, pp. 1197-208, 2016.
G. Lombardi, Berti, V., Tedde, A., Bagnoli, S., Piaceri, I., Polito, C., Lucidi, G., Ferrari, C., Ginestroni, A., Moretti, M., Pupi, A., Nacmias, B., and Sorbi, S., Low Florbetapir PET Uptake and Normal Aβ1-42 Cerebrospinal Fluid in an APP Ala713Thr Mutation Carrier., J Alzheimers Dis, vol. 57, no. 3, pp. 697-703, 2017.

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