Alzheimer Disease
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Amyloid beta-Peptides
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Amyloid beta-Protein Precursor
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Amyloid Precursor Protein Secretases
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Animals
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Benzamides
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Cell Line
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Disease Models, Animal
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Gene Knockdown Techniques
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Humans
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Imatinib Mesylate
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Mice
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Peptide Fragments
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Piperazines
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Proteins
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Pyrimidines
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
Receptor, Notch1
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.
RNA Interference
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P.,
“Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”,
Nature, vol. 467, no. 7311, pp. 95-8, 2010.