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Disease Models, Animal
K. R. LeVault, Tischkau, S. A., and Brewer, G. J., “Circadian Disruption Reveals a Correlation of an Oxidative GSH/GSSG Redox Shift with Learning and Impaired Memory in an Alzheimer's Disease Mouse Model.”, J Alzheimers Dis, vol. 49, no. 2, pp. 301-16, 2016.
A. de Calignon, Polydoro, M., Suárez-Calvet, M., William, C., Adamowicz, D. H., Kopeikina, K. J., Pitstick, R., Sahara, N., Ashe, K. H., Carlson, G. A., Spires-Jones, T. L., and Hyman, B. T., “Propagation of tau pathology in a model of early Alzheimer's disease.”, Neuron, vol. 73, no. 4, pp. 685-97, 2012.
D. A. Gimbel, Nygaard, H. B., Coffey, E. E., Gunther, E. C., Laurén, J., Gimbel, Z. A., and Strittmatter, S. M., “Memory impairment in transgenic Alzheimer mice requires cellular prion protein.”, J Neurosci, vol. 30, no. 18, pp. 6367-74, 2010.
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P., “Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”, Nature, vol. 467, no. 7311, pp. 95-8, 2010.
A. Griciuc, Serrano-Pozo, A., Parrado, A. R., Lesinski, A. N., Asselin, C. N., Mullin, K., Hooli, B., Choi, S. Hoon, Hyman, B. T., and Tanzi, R. E., “Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta.”, Neuron, vol. 78, no. 4, pp. 631-43, 2013.
A. Ezra, Rabinovich-Nikitin, I., Rabinovich-Toidman, P., and Solomon, B., “Multifunctional Effect of Human Serum Albumin Reduces Alzheimer's Disease Related Pathologies in the 3xTg Mouse Model.”, J Alzheimers Dis, vol. 50, no. 1, pp. 175-88, 2016.
J. Gräff, Rei, D., Guan, J. - S., Wang, W. - Y., Seo, J., Hennig, K. M., Nieland, T. J. F., Fass, D. M., Kao, P. F., Kahn, M., Su, S. C., Samiei, A., Joseph, N., Haggarty, S. J., Delalle, I., and Tsai, L. - H., “An epigenetic blockade of cognitive functions in the neurodegenerating brain.”, Nature, vol. 483, no. 7388, pp. 222-6, 2012.
A. W. Bero, Yan, P., Roh, J. Hoon, Cirrito, J. R., Stewart, F. R., Raichle, M. E., Lee, J. - M., and Holtzman, D. M., “Neuronal activity regulates the regional vulnerability to amyloid-β deposition.”, Nat Neurosci, vol. 14, no. 6, pp. 750-6, 2011.
K. Nunez, Kay, J., Krotow, A., Tong, M., Agarwal, A. R., Cadenas, E., and de la Monte, S. M., “Cigarette Smoke-Induced Alterations in Frontal White Matter Lipid Profiles Demonstrated by MALDI-Imaging Mass Spectrometry: Relevance to Alzheimer's Disease.”, J Alzheimers Dis, vol. 51, no. 1, pp. 151-63, 2016.
V. Bonet-Costa, Herranz-Pérez, V., Blanco-Gandía, M. C., Mas-Bargues, C., Inglés, M., Garcia-Tarraga, P., Rodriguez-Arias, M., Miñarro, J., Borras, C., Garcia-Verdugo, J. Manuel, and Viña, J., “Clearing Amyloid-β through PPARγ/ApoE Activation by Genistein is a Treatment of Experimental Alzheimer's Disease.”, J Alzheimers Dis, vol. 51, no. 3, pp. 701-11, 2016.
D. Fang, Zhang, Z., Li, H., Yu, Q., Douglas, J. T., Bratasz, A., Kuppusamy, P., and Yan, S. ShiDu, “Increased Electron Paramagnetic Resonance Signal Correlates with Mitochondrial Dysfunction and Oxidative Stress in an Alzheimer's disease Mouse Brain.”, J Alzheimers Dis, vol. 51, no. 2, pp. 571-80, 2016.
S. Simonovitch, Schmukler, E., Bespalko, A., Iram, T., Frenkel, D., Holtzman, D. M., Masliah, E., Michaelson, D. M., and Pinkas-Kramarski, R., “Impaired Autophagy in APOE4 Astrocytes.”, J Alzheimers Dis, vol. 51, no. 3, pp. 915-27, 2016.
S. V. Ovsepian and O'Leary, V. B., “Neuronal activity and amyloid plaque pathology: an update.”, J Alzheimers Dis, vol. 49, no. 1, pp. 13-9, 2016.
T. Minh Do, Dodacki, A., Alata, W., Calon, F., Nicolic, S., Scherrmann, J. - M., Farinotti, R., and Bourasset, F., “Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).”, J Alzheimers Dis, vol. 49, no. 2, pp. 287-300, 2016.
Z. Rusznák, Kim, W. Scott, Hsiao, J. - H. T., Halliday, G. M., Paxinos, G., and Fu, Y. H., “Early in vivo Effects of the Human Mutant Amyloid-β Protein Precursor (hAβPPSwInd) on the Mouse Olfactory Bulb.”, J Alzheimers Dis, vol. 49, no. 2, pp. 443-57, 2016.
M. Fà, Zhang, H., Staniszewski, A., Saeed, F., Shen, L. W., Schiefer, I. T., Siklos, M. I., Tapadar, S., Litosh, V. A., Libien, J., Petukhov, P. A., Teich, A. F., Thatcher, G. R. J., and Arancio, O., “Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 3, pp. 707-21, 2016.
P. Jul, Volbracht, C., de Jong, I. E. M., Helboe, L., Elvang, A. Brandt, and Pedersen, J. Torleif, “Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model.”, J Alzheimers Dis, vol. 49, no. 3, pp. 783-95, 2016.
M. Díaz, Fabelo, N., Casañas-Sánchez, V., Marin, R., Gómez, T., Quinto-Alemany, D., and Pérez, J. A., “Hippocampal Lipid Homeostasis in APP/PS1 Mice is Modulated by a Complex Interplay Between Dietary DHA and Estrogens: Relevance for Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 2, pp. 459-81, 2016.
A. Savastano, Klafki, H., Haußmann, U., Oberstein, T. Jan, Muller, P., Wirths, O., Wiltfang, J., and Bayer, T. A., “N-truncated Aβ2-X starting with position two in sporadic Alzheimer's disease cases and two Alzheimer mouse models.”, J Alzheimers Dis, vol. 49, no. 1, pp. 101-10, 2016.
Y. Shan, Wang, D. - D., Xu, Y. - X., Wang, C., Cao, L., Liu, Y. - S., and Zhu, C. - Q., “Aging as a Precipitating Factor in Chronic Restraint Stress-Induced Tau Aggregation Pathology, and the Protective Effects of Rosmarinic Acid.”, J Alzheimers Dis, vol. 49, no. 3, pp. 829-44, 2016.
G. - H. Lee, Jang, B., Choi, H. - S., Kim, H. - J., Park, J. - H., Jeon, Y. - C., Carp, R. I., Kim, Y. - S., and Choi, E. - K., “Upregulation of Connexin 43 Expression Via C-Jun N-Terminal Kinase Signaling in Prion Disease.”, J Alzheimers Dis, vol. 49, no. 4, pp. 1005-19, 2016.
R. Weissmann, Hüttenrauch, M., Kacprowski, T., Bouter, Y., Pradier, L., Bayer, T. A., Kuss, A. W., and Wirths, O., “Gene Expression Profiling in the APP/PS1KI Mouse Model of Familial Alzheimer's Disease.”, J Alzheimers Dis, vol. 50, no. 2, pp. 397-409, 2016.
R. Yu, Deochand, C., Krotow, A., Leão, R., Tong, M., Agarwal, A. R., Cadenas, E., and de la Monte, S. M., “Tobacco Smoke-Induced Brain White Matter Myelin Dysfunction: Potential Co-Factor Role of Smoking in Neurodegeneration.”, J Alzheimers Dis, vol. 50, no. 1, pp. 133-48, 2016.
S. Lim, Choi, J. Gyu, Moon, M., Kim, H. Geun, Lee, W., Bak, H. - R., Sung, H., Park, C. Hye, Kim, S. Yeou, and Oh, M. Sook, “An Optimized Combination of Ginger and Peony Root Effectively Inhibits Amyloid-β Accumulation and Amyloid-β-Mediated Pathology in AβPP/PS1 Double-Transgenic Mice.”, J Alzheimers Dis, vol. 50, no. 1, pp. 189-200, 2016.
N. Bartolotti, Segura, L., and Lazarov, O., “Diminished CRE-Induced Plasticity is Linked to Memory Deficits in Familial Alzheimer's Disease Mice.”, J Alzheimers Dis, vol. 50, no. 2, pp. 477-89, 2016.

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