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Disease Progression
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M., “The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”, J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
A. de Calignon, Polydoro, M., Suárez-Calvet, M., William, C., Adamowicz, D. H., Kopeikina, K. J., Pitstick, R., Sahara, N., Ashe, K. H., Carlson, G. A., Spires-Jones, T. L., and Hyman, B. T., “Propagation of tau pathology in a model of early Alzheimer's disease.”, Neuron, vol. 73, no. 4, pp. 685-97, 2012.
T. E. Golde, Schneider, L. S., and Koo, E. H., “Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shift.”, Neuron, vol. 69, no. 2, pp. 203-13, 2011.
C. R. Jack, Knopman, D. S., Weigand, S. D., Wiste, H. J., Vemuri, P., Lowe, V., Kantarci, K., Gunter, J. L., Senjem, M. L., Ivnik, R. J., Roberts, R. O., Rocca, W. A., Boeve, B. F., and Petersen, R. C., “An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease.”, Ann Neurol, vol. 71, no. 6, pp. 765-75, 2012.
J. Li, Wang, Y. J., Zhang, M., Xu, Z. Q., Gao, C. Y., Fang, C. Q., Yan, J. C., and Zhou, H. D., “Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease.”, Neurology, vol. 76, no. 17, pp. 1485-91, 2011.
M. Sattlecker, Khondoker, M., Proitsi, P., Williams, S., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., and Dobson, R. Jb, “Longitudinal Protein Changes in Blood Plasma Associated with the Rate of Cognitive Decline in Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 4, pp. 1105-14, 2016.
H. Hochstetler, Trzepacz, P. T., Wang, S., Yu, P., Case, M., Henley, D. B., Degenhardt, E., Leoutsakos, J. - M., and Lyketsos, C. G., “Empirically Defining Trajectories of Late-Life Cognitive and Functional Decline.”, J Alzheimers Dis, vol. 50, no. 1, pp. 271-82, 2016.
A. Oulhaj, Jernerén, F., Refsum, H., A Smith, D., and de Jager, C. A., “Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment.”, J Alzheimers Dis, vol. 50, no. 2, pp. 547-57, 2016.
H. Braak, Thal, D. R., Ghebremedhin, E., and Del Tredici, K., “Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years.”, J Neuropathol Exp Neurol, vol. 70, no. 11, pp. 960-9, 2011.
G. M. McKhann, Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., Mohs, R. C., Morris, J. C., Rossor, M. N., Scheltens, P., Carrillo, M. C., Thies, B., Weintraub, S., and Phelps, C. H., “The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.”, Alzheimers Dement, vol. 7, no. 3, pp. 263-9, 2011.
P. S. Aisen, Andrieu, S., Sampaio, C., Carrillo, M., Khachaturian, Z. S., Dubois, B., Feldman, H. H., Petersen, R. C., Siemers, E., Doody, R. S., Hendrix, S. B., Grundman, M., Schneider, L. S., Schindler, R. J., Salmon, E., Potter, W. Z., Thomas, R. G., Salmon, D., Donohue, M., Bednar, M. M., Touchon, J., and Vellas, B., “Report of the task force on designing clinical trials in early (predementia) AD.”, Neurology, vol. 76, no. 3, pp. 280-6, 2011.
M. Babić Leko, Borovečki, F., Dejanović, N., Hof, P. R., and Šimić, G., “Predictive Value of Cerebrospinal Fluid Visinin-Like Protein-1 Levels for Alzheimer's Disease Early Detection and Differential Diagnosis in Patients with Mild Cognitive Impairment.”, J Alzheimers Dis, vol. 50, no. 3, pp. 765-78, 2016.
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R., “Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”, J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
J. C. Triplett, Swomley, A. M., Cai, J., Klein, J. B., and D Butterfield, A., “Quantitative phosphoproteomic analyses of the inferior parietal lobule from three different pathological stages of Alzheimer's disease.”, J Alzheimers Dis, vol. 49, no. 1, pp. 45-62, 2016.
B. Yoon, Shim, Y. S., Park, H. - K., Park, S. Ah, Choi, S. Hye, and Yang, D. Won, “Predictive factors for disease progression in patients with early-onset Alzheimer's disease.”, J Alzheimers Dis, vol. 49, no. 1, pp. 85-91, 2016.
Y. Pan, Liu, R., Terpstra, E., Wang, Y., Qiao, F., Wang, J., Tong, Y., and Pan, B., “Dysregulation and diagnostic potential of microRNA in Alzheimer's disease.”, J Alzheimers Dis, vol. 49, no. 1, pp. 1-12, 2016.
B. Seok Ye, Jang, E. Young, Kim, S. Yoon, Kim, E. - J., Park, S. Ah, Lee, Y., Hong, C. Hyung, Choi, S. Hye, Yoon, B., Yoon, S. Jin, Na, H. Ri, Lee, J. - H., Jeong, J. H., Kim, H. Jin, Na, D. L., and Seo, S. Won, “Unstable Body Mass Index and Progression to Probable Alzheimer's Disease Dementia in Patients with Amnestic Mild Cognitive Impairment.”, J Alzheimers Dis, vol. 49, no. 2, pp. 483-91, 2016.
S. Tu, Leyton, C. E., Hodges, J. R., Piguet, O., and Hornberger, M., “Divergent Longitudinal Propagation of White Matter Degradation in Logopenic and Semantic Variants of Primary Progressive Aphasia.”, J Alzheimers Dis, vol. 49, no. 3, pp. 853-61, 2016.
S. Hsieh, Leyton, C. E., Caga, J., Flanagan, E., Kaizik, C., O'Connor, C. M., Kiernan, M. C., Hodges, J. R., Piguet, O., and Mioshi, E., “The Evolution of Caregiver Burden in Frontotemporal Dementia with and without Amyotrophic Lateral Sclerosis.”, J Alzheimers Dis, vol. 49, no. 3, pp. 875-85, 2016.
J. Ku Chung, Plitman, E., Nakajima, S., M Chakravarty, M., Caravaggio, F., Takeuchi, H., Gerretsen, P., Iwata, Y., Patel, R., Mulsant, B. H., and Graff-Guerrero, A., “Depressive Symptoms and Small Hippocampal Volume Accelerate the Progression to Dementia from Mild Cognitive Impairment.”, J Alzheimers Dis, vol. 49, no. 3, pp. 743-54, 2016.
H. F. M. Rhodius-Meester, Koikkalainen, J., Mattila, J., Teunissen, C. E., Barkhof, F., Lemstra, A. W., Scheltens, P., Lötjönen, J., and van der Flier, W. M., “Integrating Biomarkers for Underlying Alzheimer's Disease in Mild Cognitive Impairment in Daily Practice: Comparison of a Clinical Decision Support System with Individual Biomarkers.”, J Alzheimers Dis, vol. 50, no. 1, pp. 261-70, 2016.
C. Lange, Suppa, P., Frings, L., Brenner, W., Spies, L., and Buchert, R., “Optimization of Statistical Single Subject Analysis of Brain FDG PET for the Prognosis of Mild Cognitive Impairment-to-Alzheimer's Disease Conversion.”, J Alzheimers Dis, vol. 49, no. 4, pp. 945-59, 2016.
G. Tosto, Monsell, S. E., Hawes, S. E., Bruno, G., and Mayeux, R., “Progression of Extrapyramidal Signs in Alzheimer's Disease: Clinical and Neuropathological Correlates.”, J Alzheimers Dis, vol. 49, no. 4, pp. 1085-93, 2016.
J. Dukart, Sambataro, F., and Bertolino, A., “Accurate Prediction of Conversion to Alzheimer's Disease using Imaging, Genetic, and Neuropsychological Biomarkers.”, J Alzheimers Dis, vol. 49, no. 4, pp. 1143-59, 2016.
C. Yang Santos, Lim, Y. Ying, Wu, W. - C., Machan, J. Timothy, Polynice, S., Schindler, R., Maruff, P., and Snyder, P. Jeffrey, “Resting-State Cardiac Workload is Related to Both Increased Neocortical Aggregation of Amyloid-β and Relative Impairments in Spatial Working Memory in Pre-Clinical Alzheimer's Disease.”, J Alzheimers Dis, vol. 50, no. 1, pp. 127-31, 2016.

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