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Receptors, Immunologic
J. L. Del-Aguila, Fernández, M. Victoria, Schindler, S., Ibanez, L., Deming, Y., Ma, S., Saef, B., Black, K., Budde, J., Norton, J., Chasse, R., Harari, O., Goate, A., Xiong, C., Morris, J. C., and Cruchaga, C., “Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.”, J Alzheimers Dis, vol. 62, no. 2, pp. 745-756, 2018.
M. Berger, Cooter, M., Roesler, A. S., Chung, S., Park, J., Modliszewski, J. L., VanDusen, K. W., J Thompson, W., Moseley, A., Devinney, M. J., Smani, S., Hall, A., Cai, V., Browndyke, J. N., Lutz, M. W., and Corcoran, D. L., “APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid.”, J Alzheimers Dis, vol. 79, no. 2, pp. 511-530, 2021.
H. Khodadadi, Salles, É. Lopes, Jarrahi, A., Costigliola, V., Khan, M. B., Yu, J. C., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M., and Baban, B., “Cannabidiol Ameliorates Cognitive Function via Regulation of IL-33 and TREM2 Upregulation in a Murine Model of Alzheimer's Disease.”, J Alzheimers Dis, vol. 80, no. 3, pp. 973-977, 2021.
C. Wu, Ma, Y. - H., Hu, H., Zhao, B., and Tan, L., “Soluble TREM2, Alzheimer's Disease Pathology, and Risk for Progression of Cerebral Small Vessel Disease: A Longitudinal Study.”, J Alzheimers Dis, vol. 92, no. 1, pp. 311-322, 2023.
S. Chand Basha, Ramaiah, M. Janaki, and Kosagisharaf, J. Rao, “Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer's Disease.”, J Alzheimers Dis, vol. 94, no. s1, pp. S319-S333, 2023.
Receptors, Laminin
E. C. Pinnock, Jovanovic, K., Pinto, M. G., Ferreira, E., Dias, B. Da Costa, Penny, C., Knackmuss, S., Reusch, U., Little, M., Schatzl, H. M., and Weiss, S. F. T., “LRP/LR Antibody Mediated Rescuing of Amyloid-β-Induced Cytotoxicity is Dependent on PrPc in Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 3, pp. 645-57, 2016.
Receptors, LDL
H. Xu, Perreau, V. M., Dent, K. A., Bush, A. I., Finkelstein, D. I., and Adlard, P. A., “Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes.”, J Alzheimers Dis, vol. 51, no. 2, pp. 471-87, 2016.
T. Minh Do, Dodacki, A., Alata, W., Calon, F., Nicolic, S., Scherrmann, J. - M., Farinotti, R., and Bourasset, F., “Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).”, J Alzheimers Dis, vol. 49, no. 2, pp. 287-300, 2016.
Receptors, N-Methyl-D-Aspartate
H. Jin, Chen, T., Li, G., Wang, C., Zhang, B., Cao, X., Sha, S., Wan, Q., and Chen, L., “Dose-Dependent Neuroprotection and Neurotoxicity of Simvastatin through Reduction of Farnesyl Pyrophosphate in Mice Treated with Intracerebroventricular Injection of Aβ 1-42.”, J Alzheimers Dis, vol. 50, no. 2, pp. 501-16, 2016.
L. Chang, Zhang, Y., Liu, J., Song, Y., Lv, A., Li, Y., Zhou, W., Yan, Z., Almeida, O. F. X., and Wu, Y., “Differential Regulation of N-Methyl-D-Aspartate Receptor Subunits is an Early Event in the Actions of Soluble Amyloid-β(1-40) Oligomers on Hippocampal Neurons.”, J Alzheimers Dis, vol. 51, no. 1, pp. 197-212, 2016.
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S., “A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”, J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Y. Huang, Shen, W., Su, J., Cheng, B., Li, D., Liu, G., Zhou, W. - X., and Zhang, Y. - X., “Modulating the Balance of Synaptic and Extrasynaptic NMDA Receptors Shows Positive Effects against Amyloid-β-Induced Neurotoxicity.”, J Alzheimers Dis, vol. 57, no. 3, pp. 885-897, 2017.
Receptors, Retinoic Acid
N. Pierrot, Lhommel, R., Quenon, L., Hanseeuw, B., Dricot, L., Sindic, C., Maloteaux, J. - M., Octavea, J. - N., and Ivanoiu, A., “Targretin Improves Cognitive and Biological Markers in a Patient with Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 2, pp. 271-6, 2016.
Receptors, Transferrin
P. Banerjee, Sahoo, A., Anand, S., Bir, A., and Chakrabarti, S., “The Oral Iron Chelator, Deferasirox, Reverses the Age-Dependent Alterations in Iron and Amyloid-β Homeostasis in Rat Brain: Implications in the Therapy of Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 3, pp. 681-93, 2016.
Receptors, Tumor Necrosis Factor, Type II
N. Ortí-Casañ, Wajant, H., H Kuiperij, B., Hooijsma, A., Tromp, L., Poortman, I. L., Tadema, N., de Lange, J. H. E., Verbeek, M. M., De Deyn, P. P., Naudé, P. J. W., and Eisel, U. L. M., “Activation of TNF Receptor 2 Improves Synaptic Plasticity and Enhances Amyloid-β Clearance in an Alzheimer's Disease Mouse Model with Humanized TNF Receptor 2.”, J Alzheimers Dis, vol. 94, no. 3, pp. 977-991, 2023.
Recognition (Psychology)
V. Bonet-Costa, Herranz-Pérez, V., Blanco-Gandía, M. C., Mas-Bargues, C., Inglés, M., Garcia-Tarraga, P., Rodriguez-Arias, M., Miñarro, J., Borras, C., Garcia-Verdugo, J. Manuel, and Viña, J., “Clearing Amyloid-β through PPARγ/ApoE Activation by Genistein is a Treatment of Experimental Alzheimer's Disease.”, J Alzheimers Dis, vol. 51, no. 3, pp. 701-11, 2016.
A. J García-Casal, Goñi-Imizcoz, M., M Perea-Bartolomé, V., Soto-Pérez, F., Smith, S. Jane, Calvo-Simal, S., and Franco-Martín, M., “The Efficacy of Emotion Recognition Rehabilitation for People with Alzheimer's Disease.”, J Alzheimers Dis, vol. 57, no. 3, pp. 937-951, 2017.
Y. Huang, Shen, W., Su, J., Cheng, B., Li, D., Liu, G., Zhou, W. - X., and Zhang, Y. - X., “Modulating the Balance of Synaptic and Extrasynaptic NMDA Receptors Shows Positive Effects against Amyloid-β-Induced Neurotoxicity.”, J Alzheimers Dis, vol. 57, no. 3, pp. 885-897, 2017.
E. J. Mason, Hussey, E. P., Molitor, R. J., Ko, P. C., Donahue, M. J., and Ally, B. A., “Family History of Alzheimer's Disease is Associated with Impaired Perceptual Discrimination of Novel Objects.”, J Alzheimers Dis, vol. 57, no. 3, pp. 735-745, 2017.
J. Mehla, Lacoursiere, S., Stuart, E., McDonald, R. J., and Mohajerani, M. H., “Gradual Cerebral Hypoperfusion Impairs Fear Conditioning and Object Recognition Learning and Memory in Mice: Potential Roles of Neurodegeneration and Cholinergic Dysfunction.”, J Alzheimers Dis, vol. 61, no. 1, pp. 283-293, 2018.
C. M. Huber, Yee, C., May, T., Dhanala, A., and Mitchell, C. S., “Cognitive Decline in Preclinical Alzheimer's Disease: Amyloid-Beta versus Tauopathy.”, J Alzheimers Dis, vol. 61, no. 1, pp. 265-281, 2018.
Recombinant Fusion Proteins
F. Pasquier, Sadowsky, C., Holstein, A., Leterme, G. Le Prince, Peng, Y., Jackson, N., Fox, N. C., Ketter, N., Liu, E., and J Ryan, M., “Two Phase 2 Multiple Ascending-Dose Studies of Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Mild-to-Moderate Alzheimer's Disease.”, J Alzheimers Dis, vol. 51, no. 4, pp. 1131-43, 2016.
Recombinant Proteins
K. Talbot, Wang, H. - Y., Kazi, H., Han, L. - Y., Bakshi, K. P., Stucky, A., Fuino, R. L., Kawaguchi, K. R., Samoyedny, A. J., Wilson, R. S., Arvanitakis, Z., Schneider, J. A., Wolf, B. A., Bennett, D. A., Trojanowski, J. Q., and Arnold, S. E., “Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.”, J Clin Invest, vol. 122, no. 4, pp. 1316-38, 2012.
Reference Standards
N. Lelental, Brandner, S., Kofanova, O., Blennow, K., Zetterberg, H., Andreasson, U., Engelborghs, S., Mroczko, B., Gabryelewicz, T., Teunissen, C., Mollenhauer, B., Parnetti, L., Chiasserini, D., Molinuevo, J. Luis, Perret-Liaudet, A., Verbeek, M. M., Andreasen, N., Brosseron, F., Bahl, J. M. C., Herukka, S. - K., Hausner, L., Frölich, L., Labonte, A., Poirier, J., Miller, A. - M., Zilka, N., Kovacech, B., Urbani, A., Suardi, S., Oliveira, C., Baldeiras, I., Dubois, B., Rot, U., Lehmann, S., Skinningsrud, A., Betsou, F., Wiltfang, J., Gkatzima, O., Winblad, B., Buchfelder, M., Kornhuber, J., and Lewczuk, P., “Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics.”, J Alzheimers Dis, vol. 52, no. 1, pp. 51-64, 2016.
Reference Values
A. Griciuc, Serrano-Pozo, A., Parrado, A. R., Lesinski, A. N., Asselin, C. N., Mullin, K., Hooli, B., Choi, S. Hoon, Hyman, B. T., and Tanzi, R. E., “Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta.”, Neuron, vol. 78, no. 4, pp. 631-43, 2013.

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