Two hundred issues and nearly twenty years have positioned JAD at the center of printed and electronic peer-reviewed publications in Alzheimer's disease, as a venue that reflects the breadth of research in the field worldwide. The launch of our new Editors' Blog series marks an opportunity for JAD to go beyond the traditional journal format of recording data to now look forward and influence the dialog on what will be done. Together with our reformatted website, JAD is repositioning itself as a major site for information on Alzheimer's disease and debate related to future directions in our field.
Our blog series will begin with postings on some of the most exciting evolving areas in our field: breakthrough innovative cell models, depression, and ethics. Roughly every 2 weeks we will host a new blog posted by thoughtful and innovative researchers in our field. Upcoming posts will include:
- Gwenn Smith has promised a post on Depression in Alzheimer’s. Her work has focused for many years on the neuropsychiatric correlates of AD and other dementias using brain imaging techniques (see, e.g., [1-3]).
- Allyson Rosen will blog on emerging ethical issues in AD research. She will focus on ethical aspects of early diagnosis, measurement of therapeutic response, and guiding decisions that restrict autonomy.
- Rudy Tanzi and Doo Yeon Kim will post on their new “Alzheimer’s in a Dish” 3-D cell culture model, developed at the Massachusetts General Hospital [4].
- Andrea Tales will provide an update on the issue of Subjective Cognitive Decline.
We look forward to everyone joining us and engaging in these discussions, and many others that we expect will follow.
References
[1] Geda YE, Schneider LS, Gitlin LN, Miller DS, Smith GS, Bell J, Evans J, Lee M, Porsteinsson A, Lanctôt KL, Rosenberg PB, Sultzer DL, Francis PT, Brodaty H, Padala PP, Onyike CU, Ortiz LA, Ancoli-Israel S, Bliwise DL, Martin JL, Vitiello MV, Yaffe K, Zee PC, Herrmann N, Sweet RA, Ballard C, Khin NA, Alfaro C, Murray PS, Schultz S, Lyketsos CG; Neuropsychiatric Syndromes Professional Interest Area of ISTAART (2013) Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future. Alzheimers Dement 9, 602-608. http://dx.doi.org/10.1016/j.jalz.2012.12.001
[2] Tighe SK, Oishi K, Mori S, Smith GS, Albert M, Lyketsos CG, Mielke MM (2012) Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer’s dementia. J Neuropsychiatry Clin Neurosci 24, 484-488. http://dx.doi.org/10.1176/appi.neuropsych.11120375.
[3] Hirao K, Pontone GM, Smith GS (2015) Molecular imaging of neuropsychiatric symptoms in Alzheimer's and Parkinson's disease. Neurosci Biobehav Rev 49, 157-170. http://www.sciencedirect.com/science/article/pii/S0149763414002954.
[4] Choi SH, Kim YH, Hebisch M, Sliwinski C, Lee S, D'Avanzo C, Chen H, Hooli B, Asselin C, Muffat J, Klee JB, Zhang C, Wainger BJ, Peitz M, Kovacs DM, Woolf CJ, Wagner SL, Tanzi RE, Kim DY (2014) A three-dimensional human neural cell culture model of Alzheimer/'s disease. Nature 515, 274-278. http://dx.doi.org/10.1038/nature13800
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