Sylvie Ricard-Blum, PhD

JAD profile

Affiliation(s): 

University Lyon 1

Areas of Interest: 

extracellular matrix, glycosaminoglycans, matricryptins, interaction networks, Alzheimer's disease

Biography & Research: 

Sylvie Ricard-Blum is Professor of Biochemistry at the University of Lyon, where she is the coordinator of the Master programme in Biochemistry and deputy director of the Interdisciplinary Sciences - Health doctoral school. Her work, based on the study of structure - interaction - function relationships, combines biochemistry, biophysics, bioinformatics and systems biology. Her laboratory has developed protein and glycosaminoglycan arrays to screen biomolecular interactions by surface plasmon resonance imaging and has built the extracellular matrix interaction database MatrixDB. Her major research interests are multimolecular complexes and interaction networks formed in the pericellular and extracellular matrix and their rewiring in the pathological contexts of Alzheimer’s disease and host-pathogen interactions. She has identified new partners of a number of extracellular proteins and glycosaminoglycans with a focus on the matricryptin endostatin and on heparan sulfate. She has been Secretary (2001-2007) and President (2008-2012, 2014) of the French Society for Matrix Biology and organized the XXIst Federation of European Connective Tissue meeting in 2008. She is a member of the Council of the International Society for Matrix Biology (ISMB), and the editor of ISMB newsletter. She is editor of the HUPO Proteomics Standard Initiative and co-chair of the HUPO-PSI Molecular Interaction group.