09-Jan-2007 - Thinking about Cognition - A new book published by IOS Press Contact: Astrid Engelen Amsterdam, January 9, 2007 – IOS Press is pleased to announce the publication of a significant work exploring human cognition and neurological disease, Thinking about Cognition: Concepts, Targets and Therapeutics. This collection of papers presented at the Fifth Solvay Pharmaceutical Conference, Miami, Florida, USA, February 2006, represents the work of recognized leaders in the field of cognition research. It provides state-of-the-art contributions on mechanisms and therapy of cognitive disorders. 100 Years after the discovery of Alzheimer’s disease, neurological diseases and psychiatric disorders represent the largest and fastest growing medical threat to an aging world population, with 2 billion affected people worldwide. While life expectancy continues to increase, advanced age may lead to deterioration of cognitive function of the brain. Although increasing knowledge about neuronal networks is transforming our view of the human brain and its function and we understand psychiatric and neurological diseases better today than ever before, novel therapies are needed to respond to the growing demand of patients for assistance with memory loss and learning impairment. In fact, it is expected that novel therapies aiming at the processing of amyloid, or at activation of glutamatergic or nicotinergic systems will be effective in improving learning and memory disturbances. Held during the year marking the 100th anniversary of the discovery of Alzheimer’s disease (AD), this conference volume stands as a comprehensive overview of the cellular and molecular mechanisms underlying cognitive impairment and explores the development of novel therapies. It integrates discoveries concerning dementia, such as mild cognitive impairment and Alzheimer’s disease associated dementia, vascular dementia, retardation syndromes, and psychiatric and neurological disorders related cognitive impairments. This book is a valuable resource for physicians, biologists and those pursuing an interest or concerned with memory impairment. As publisher of the Journal of Alzheimer’s Disease andthe landmarkbook marking the centennial of the Alois Alzheimer's discovery, Alzheimer's Disease: A Century of Scientific and Clinical Research (edited by G. Perry, J. Avila, J. Kinoshita and M.A. Smith), as well as an extensive list of titles in cognitive science and neurological medicine, IOS Press continues to publish important contributions from leading AD researchers worldwide. Contact a.engelen@iospress.nl or market@iospress.nl or visit www.iospress.nl for additional information. Thinking about Cognition: Concepts, Targets and Therapeutics Table of Contents Preface Conference Preface Keynote Lecture – The Meaning of Cognition in our Society and Health Care Systems Age-Associated Memory Impairment Cognition in Alzheimer’s Disease and Related Disorders Cognitive Deficits as a Core Feature of Schizophrenia Cognition in Depression and Mania Linking Pre-Clinical and Clinical Approaches to Therapy for Cognitive Dysfunction in Neuropsychiatric and Neurodegenerative Disorders Pre-Clinical Models of Cognition: The Role of the Cannabis Subtype 1 Receptor Modulation of N-Methyl-D-Aspartate Receptor Function as a Novel Approach for Development of Antipsychotic Agents Molecular and Cellular Cognition: Mechanisms of Plasticity Treatment of Cognitive Deficits: Schizophrenia as an Example Functional Imaging of Cognition Related Brain Circuitry in Health and in Schizophrenia Clinical Proof for Cognition Enhancers: Pitfalls and Possibilities About IOS Press |