Title | Influence of Incipient Dementia on Hospitalization for Primary Care Sensitive Conditions: A Population-Based Cohort Study. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Pimouguet, C, Rizzuto, D, Fastbom, J, Lagergren, M, Fratiglioni, L, Xu, W |
Journal | J Alzheimers Dis |
Volume | 52 |
Issue | 1 |
Pagination | 213-22 |
Date Published | 2016 03 08 |
ISSN | 1875-8908 |
Keywords | Acute Disease, Age Factors, Aged, Aged, 80 and over, Chronic Disease, Dementia, Female, Follow-Up Studies, Hospitalization, Humans, Logistic Models, Longitudinal Studies, Male, Primary Health Care, Registries, Risk, Sensitivity and Specificity, Socioeconomic Factors, Sweden |
Abstract | BACKGROUND: Studies have reported that moderate/severe stages of dementia are linked to increased hospitalization rates, but little is known about the influence of incipient dementia on hospitalizations for primary care sensitive conditions (PCSCs). OBJECTIVE: To examine the associations between incipient dementia and hospitalization outcomes, including all-cause and PCSC hospitalization. METHODS: A total of 2,268 dementia-free participants in the Swedish National study on Aging and Care-Kungsholmen were interviewed and clinically examined at baseline. Participants aged ≥78 years were followed for 3 years, and those aged 60-72 years, for 6 years. Number of hospitalizations was retrieved from the National Patient Register. Dementia was diagnosed in accordance with Diagnostic and Statistical Manual of Mental Disorders-IV criteria. Hospitalization outcomes were compared in participants who did and did not develop dementia. Zero-inflated Poisson regressions and logistic regressions were used in data analysis. RESULTS: During the follow-up, 175 participants developed dementia. The unadjusted PCSC admission rate was 88.2 per 1000 person-years in those who developed dementia and 25.6 per 1000 person-years in those who did not. In the fully adjusted logistic regression model, incipient dementia was associated with an increased risk of hospitalization for PCSCs (OR = 2.3, 95% CI 1.3-3.9) but not with the number of hospitalizations or with all-cause hospitalization. Risks for hospitalization for diabetes, congestive heart failure, and pyelonephritis were higher in those who developed dementia than in those who did not. About 10% participants had a PCSC hospitalization attributable to incipient dementia. CONCLUSION: People with incipient dementia are more prone to hospitalization for PCSCs but not to all-cause hospitalization. |
DOI | 10.3233/JAD-150853 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 27060943 |