AIAD Vol.8Jack de la Torre blogCOVID-19 contentPSPBook and manIL-33AIAD Vol.7 (TBI)Plaques2020 Alzheimer AwardGABAJAD70:s1 IRNDPprionJAD Reports (updated)overview

This new book, edited by Lilian Calderón-Garcidueñas, is a compilation of work by researchers intent on revealing the links between air pollution and neurodegeneration. For details & to order, click the image or go here

What is the Purpose of Medicine When Dealing with Incurable Alzheimer’s Disease?

by Jack de la Torre, MD, PhD

COVID-19 content in JAD is openly available. Read all content including the editorial by JAD's Editor-in-Chief George Perry, in which he calls out for careful study to determine the numbers of AD patients infected and dying of COVID-19, via:

Neurofibrillary tangle and tufted astrocytes evidenced with different markers of the tau protein and counterstained with thiazine red dye in a PSP case. From Martínez-Maldonado et al., JAD 79(4).

Journal of Alzheimer's Disease

is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease.


Brain tissues from 5xFAD mice model of Alzheimer’s disease showed that CBD treatment was able to increase the expression of IL-33 (red) in brain, mainly by astrocytes (green). From Khodadadi et al., JAD80(3).

This book, edited by Rudy J. Castellani, covers the relationship between neurodegenerative disease and neurotrauma through traumatic brain injury, and offers targets for therapy. For details & to order, click the image or go to: 

Aβ plaques formation and microglia activation following different age in APP/PS1 mice and wild-type littermates. From Qiu et al., JAD81(2).

The 2020 Alzheimer Award goes to Christin Nance, BA, and Sarah Banks, PhD, as co-authors of the winning JAD paper: "The Pathology of Rapid Cognitive Decline in Clinically Diagnosed AD." For more details, click the image or go to: 

Immunohistochemical co-localization of GABA transporter 1 (GAT1) and activated astrocytes (GFAP) in suprachiasmatic nucleus of 18 month old wild type and transgenic (TG) mouse model of AD. From Eeza et al., JAD81(2).

JAD's open access IRNDP special issue features research from around the globe examining the potential risk factors for dementia. The issue has been compiled by guest editors Kaarin Anstey and Ruth Peters. VIEW CONTENT

Prion plaques (green channel) with phosphorylated tau (red channel) in the cerebellum from a case with spongiform encephalopathy. Low (left) and high (right) magnification. From Gómez-López et al., JAD81(2).

JAD Reports is our fully open access international, multidisciplinary journal dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer's disease. View new content

An overview of central insulin resistance and its connections to other Alzheimer’s disease hypotheses. Consistent findings converge towards dysfunctional insulin signaling in the brain as a common and unifying link between traditional and current hypotheses. From Alves et al., JAD82(1).

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