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27 July 2021

Keystone Bio Announces Groundbreaking Data offering a More Complete Explanation of P. Gingivalis Toxic Virulence Factors

Keystone Bio presents a detailed review of the literature shows incomplete human and animal model study design(s) to support the “local” gingipains AD brain model, but rather using new data and existing publication(s) - support a “Peripheral” model of Pg blood-transported toxic virulence factors/OMVs as the major delivery mechanism into the brain. This can now be integrated into a more unifying “Concept” and explanation for the “Infection Hypothesis” for Alzheimer’s Disease (AD) and other Dementia-related disease(s).

22 June 2021

TV Ads for Prescription Drugs Linked to Higher Utilization Rates Among Seniors

The US is one of the only nations in the world that allows pharmaceutical companies to advertise directly to patients: now, TV ads have been linked with higher utilization rates for certain prescription drugs, especially among older patients. This is according to a study published in JAD and authored by Professor Robin Feldman of the University of California Hastings College of Law.

18 June 2021

Depression, Tau Deposits Seen in Subset of Middle-Aged Persons

Mitzi M. Gonzales

Middle-aged people with depressive symptoms who carry a genetic variation called apolipoprotein (APOE) ε4 may be more at risk to develop tau protein accumulations in the brain’s emotion- and memory-controlling regions, a new study by researchers from The University of Texas Health Science Center at San Antonio and collaborating institutions suggests.

27 April 2021

The Greener the Neighborhood, the Lower Risk of Alzheimer’s Disease and Dementias

University of Miami

A new University of Miami Miller School of Medicine-led study examined the relationship of neighborhood greenness, such as trees, shrubs, or grass, to Alzheimer’s disease, Non-Alzheimer’s dementia, and Alzheimer’s disease and related dementia. The study found that a greater presence of neighborhood greenness was associated with a lower prevalence of Alzheimer’s disease by 20% and non-Alzheimer's disease by 11%.

27 April 2021

Chronic Pain and Other Life Experiences May Contribute to Brain Matter Loss

Photo credit: Dr. Jared Tanner

A new University of Florida study of non-Hispanic Black and non-Hispanic white adults links chronic knee pain and key demographic factors to differences in areas of the brain tied to memory. Participants who reported higher stages of pain and lower levels of income and education and less access to health insurance had thinner gray matter in these regions than those also experiencing higher stages of pain but who reported higher levels of income, education and greater access to health insurance.

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