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12 December 2024

Therapeutic Trials in Alzheimer’s Disease: Where Are We Now?

Journal of Alzheimer's Disease

Alzheimer’s disease (AD), the most common form of dementia among older adults, remains a major scientific and clinical challenge, particularly regarding its early diagnosis and treatment. Decades of significant efforts have been made to find the cause(s), pathogenic mechanisms, biomarkers for early detection, and treatment of AD. A new collection of papers released simultaneously in the Journal of Alzheimer’s Disease and its companion book series Advances in Alzheimer’s Disease provides an in-depth overview and assessment of the state of the art of treatments and their varying degrees of success and the research behind them.

10 December 2024

Journal of Alzheimer’s Disease publishes key UNTHSC study on biomarkers in diverse populations

Lubnaa Abdullah

A team from the University of North Texas Health Science Center at Fort Worth has had a key study published in the Journal of Alzheimer’s Disease. Lubnaa Abdullah, Psy.D., ABPP, Assistant Professor within the Department of Family and Osteopathic Manipulative Medicine at the Texas College of Osteopathic Medicine and Fan Zhang, PhD, James Hall, PhD, and Sid O’Bryant, PhD. conducted the largest characterization of plasma neurofilament light chain (NfL) in community-dwelling non-Hispanic Blacks.

22 November 2024

New Study Highlights Physician Perspectives on Emerging Anti-Amyloid Treatments for Alzheimer’s Disease in Israel

In a recent study, Tel Aviv Sourasky Medical Center has shed light on physician attitudes toward novel anti-amyloid treatments (ATT) for Alzheimer’s disease (AD), revealing a spectrum of opinions across key specialties. With Israel’s health system structured to provide universal healthcare, the high out-of-pocket costs for new AD therapies have raised questions among medical professionals about the feasibility and practicality of implementing these treatments.

12 September 2024

Research Spotlight: Implementation of a Lifestyle Dementia Prevention Intervention

Ryan Andrew Mace, PhD

This intervention is a virtual, group-based program for older patients (age 60+) with subjective cognitive decline who are at risk for AD/ADRD. Group members learn mindfulness and behavioral strategies to set goals to improve physical activity, sleep, nutrition, and other lifestyle factors linked to lower rates of AD/ADRD. The goal of our study was to qualitatively identify the challenges and supportive factors impacting the acceptability, appropriateness and feasibility of this intervention within the healthcare setting based on focus groups with healthcare professionals.

14 August 2024

Possible explanation for link between diabetes and Alzheimer's

Olov Rolandsson

People with type 2 diabetes are at increased risk of Alzheimer's disease and other adverse cognitive health issues. A new study conducted at by Umeå University, Sweden, shows that the reason for the correlation may be that people with type 2 diabetes have more difficulty getting rid of a protein that potentially increases the likelihood of contracting the disease.

9 July 2024

Robert A. Rissman, PhD, Receives the 2024 Alzheimer Award

Robert Rissman

The Journal of Alzheimer’s Disease (JAD) is pleased to announce that Robert A. Rissman, PhD, University of Southern California, is the recipient of the 2024 Alzheimer Award. He is lead author of the groundbreaking article “Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer’s Disease.” The award is proudly sponsored by JAD’s publisher IOS Press, now part of Sage.

6 July 2024

Groundbreaking Ecosystem Map Reveals Innovative Collaborations, Care Pathways, and Technologies for Dementia

Dementia Ideal Care Map

A new Journal of Alzheimer's Disease article unveils an innovative tool demonstrating how key sectors and technologies can positively impact people living with dementia. The article provides a visual summary of dementia best practices from around the world in one compact tool for everyone in the dementia ecosystem—including people living with dementia; their family, friends, and communities; policymakers, employers, health system leaders, clinicians, social services providers, educators; researchers, technology entrepreneurs, and investors.

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