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14 January 2021

Approximately Half of AD Dementia Cases are Mild, One-fifth are Severe

What percent of patients with Alzheimer’s Disease currently have severe dementia? Do more people have mild disease? Or are the majority suffering with moderate dementia? A new study using data from the Framingham Heart Study sheds light on these trends. Boston University School of Medicine researchers have found that slightly more than half (50.4 percent) of cases are mild, just under one-third (30.3 percent) of cases are moderate and 19.3 percent are severe cases.

25 November 2020

Link Between Alzheimer's Disease and Gut Microbiota is Confirmed

Prof. Giovanni Frisoni and Dr. Moira Marizzoni

A team from the University of Geneva and the University Hospitals of Geneva in Switzerland, together with Italian colleagues from the National Research and Care Center for Alzheimer's and Psychiatric Diseases Fatebenefratelli in Brescia, University of Naples and the IRCCS SDN Research Center in Naples, confirm the correlation, in humans, between an imbalance in the gut microbiota and the development of amyloid plaques in the brain, which are at the origin of the neurodegenerative disorders characteristic of Alzheimer's disease.

10 November 2020

New Study Finds a Link Between Sleep Apnea and Increased Risk of Dementia

A new study by Monash University has found that obstructive sleep apnea (OSA) has been linked to an increased risk of dementia. The study, published in JAD, and led by Dr Melinda Jackson from the Turner Institute for Brain and Mental Health, found that severe OSA is linked to an increase in a protein, called beta-amyloid, that builds up on the walls of the arteries in the brain and increases the risk of dementia.

10 November 2020

Psychological Status Rather Than Cognitive Status is Associated with Incorrect Perception of Risk of Falling in Patients with Moderate Stage Dementia

Ilona Dutzi and Klaus Hauer

Dementia is associated with an impaired self-perception with potentially harmful consequences for health status and clinical risk classification in this patient group with an extraordinary high risk of falling. A new study published in the JAD indicates that psychological factors such as anxiety or fear of falling, cognitive sub-performances such as executive functions, as well as behavioral strategies such as support seeking and interplay with other risk factors should be considered when risk of falling is documented in PWD.

9 November 2020

A Randomized Clinical Trial of Greek High Phenolic Early Harvest Extra Virgin Olive Oil in Mild Cognitive Impairment: the MICOIL Pilot Study

Greek researchers and clinicians investigated for the first time the effect of High Phenolic Early Harvest Extra Virgin Olive Oil versus Moderate Phenolic and Mediterranean Diet as a therapeutic pharmaceutical natural compound for older adults with amnestic Mild Cognitive Impairment. While there is no treatment for MCI and symptomatic only treatment for AD, the global effort against cognitive disorders is focused on early detection and management of AD at the stage of aMCI.

21 October 2020

New Vaccine Targeting Toxic Amyloid-β Could Help halt Alzheimer’s Disease Progression, Preclinical Study Finds

Our immune system’s capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in people over age 65. At the same time, research has shown that immunotherapy targeting neurotoxic forms of the peptide amyloid beta (oligomeric Aβ) may halt the progression of Alzheimer’s disease, the most common age-related neurodegenerative disease.

15 October 2020

Brain Stimulation Improves Condition of Patients with Alzheimer's

A VA pilot study finds that a brain stimulation therapy provided to patients with Alzheimer’s disease improved their state of apathy, a profound loss of motivation and initiative and a feeling of social withdrawal. Apathy is the most common behavioral problem in people with Alzheimer’s disease, the No. 1 form of dementia. The results appeared online in the Journal of Alzheimer’s Disease on Oct. 13, 2020.

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