25 November 2020
A team from the University of Geneva and the University Hospitals of Geneva in Switzerland, together with Italian colleagues from the National Research and Care Center for Alzheimer's and Psychiatric Diseases Fatebenefratelli in Brescia, University of Naples and the IRCCS SDN Research Center in Naples, confirm the correlation, in humans, between an imbalance in the gut microbiota and the development of amyloid plaques in the brain, which are at the origin of the neurodegenerative disorders characteristic of Alzheimer's disease.
10 November 2020
A new study by Monash University has found that obstructive sleep apnea (OSA) has been linked to an increased risk of dementia. The study, published in JAD, and led by Dr Melinda Jackson from the Turner Institute for Brain and Mental Health, found that severe OSA is linked to an increase in a protein, called beta-amyloid, that builds up on the walls of the arteries in the brain and increases the risk of dementia.
10 November 2020
Psychological Status Rather Than Cognitive Status is Associated with Incorrect Perception of Risk of Falling in Patients with Moderate Stage Dementia
Dementia is associated with an impaired self-perception with potentially harmful consequences for health status and clinical risk classification in this patient group with an extraordinary high risk of falling. A new study published in the JAD indicates that psychological factors such as anxiety or fear of falling, cognitive sub-performances such as executive functions, as well as behavioral strategies such as support seeking and interplay with other risk factors should be considered when risk of falling is documented in PWD.
9 November 2020
A Randomized Clinical Trial of Greek High Phenolic Early Harvest Extra Virgin Olive Oil in Mild Cognitive Impairment: the MICOIL Pilot Study
Greek researchers and clinicians investigated for the first time the effect of High Phenolic Early Harvest Extra Virgin Olive Oil versus Moderate Phenolic and Mediterranean Diet as a therapeutic pharmaceutical natural compound for older adults with amnestic Mild Cognitive Impairment. While there is no treatment for MCI and symptomatic only treatment for AD, the global effort against cognitive disorders is focused on early detection and management of AD at the stage of aMCI.
21 October 2020
New Vaccine Targeting Toxic Amyloid-β Could Help halt Alzheimer’s Disease Progression, Preclinical Study Finds
Our immune system’s capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in people over age 65. At the same time, research has shown that immunotherapy targeting neurotoxic forms of the peptide amyloid beta (oligomeric Aβ) may halt the progression of Alzheimer’s disease, the most common age-related neurodegenerative disease.
15 October 2020
A VA pilot study finds that a brain stimulation therapy provided to patients with Alzheimer’s disease improved their state of apathy, a profound loss of motivation and initiative and a feeling of social withdrawal. Apathy is the most common behavioral problem in people with Alzheimer’s disease, the No. 1 form of dementia. The results appeared online in the Journal of Alzheimer’s Disease on Oct. 13, 2020.
14 October 2020
Older people without cognitive problems who experience a fall may have undetected neurodegeneration in their brains that puts them at high risk of developing Alzheimer’s dementia, according to a study from Washington University School of Medicine in St. Louis.
1 October 2020
Subtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete daily activities, such as managing medications or finances and other essential activities. Writing in the September 29, 2020 online issue of the Journal of Alzheimer’s Disease, researchers at University of California San Diego School of Medicine, with colleagues elsewhere, linked poorer cognitive performance in a single testing with subsequent greater risk for impaired daily life activities nearly a decade later.
21 September 2020
The ongoing COVID-19 pandemic has substantially affected patients with dementia and their caregivers. Owing to the restrictive measures taken worldwide to block the spread of COVID-19 outbreaks, patients with dementia and their caregivers have not been able to receive the usual support and care. Based on the hypothesis that patients with severe dementia tend to be unaware of the COVID-19 outbreak and hence may be less depressed, we compared the rate of recognition of the COVID-19 outbreak and resultant depressive tendencies between patients with mild dementia and those with severe dementia.
17 September 2020
The CABLE Study: Green Tea Consumption May Help Fend Off Cognitive Decline by Affecting Alzheimer’s Disease Tau Pathology
A team from the Qingdao University and Fudan University of China recruits more than 700 older adults aged 40 years or older, investigates their drinking tea habits, and assesses their cognitive function and especially alterations of aging brain pathology, i.e., Alzheimer’s disease.