13 February 2019
No Association Between Antiepileptic Drug Use and Dementia Risk
Epilepsy is a common neurological condition with a prevalence of around 2%. Many antiepileptic drugs are available to prevent epileptic seizures, allowing up to 80 percent of patients to become seizure-free. However, previous research has found a positive association between the use of AEDs and dementia.
28 January 2019
In Life and Death, Alzheimer’s Disease Looks Different among Hispanic Patients
Researchers at Shiley-Marcos Alzheimer’s Disease Research Center (ADRC), part of University of California San Diego School of Medicine, report that autopsies of patients diagnosed with Alzheimer’s disease (AD) when they were alive – and confirmed by autopsy – indicate many cognitive issues symptomatic of the condition are less noticeable in living Hispanic patients.
17 January 2019
Psychological Distress is a Risk Factor for Dementia: Results from a Danish Population-Based Study
A new study suggests that vital exhaustion, which can be perceived as an indicator of psychological distress, is a risk factor for future risk of dementia. Researchers from the Department of Public Health, University of Copenhagen have, in collaboration with the National Research Centre for the Working Environment, and the Danish Dementia Research Centre, shown that being distressed in late midlife is associated with a higher risk of dementia in later life.
21 December 2018
Air Pollution in Mexico City is Associated with the Development of Alzheimer's Disease in Children and Young Adults
A new study by researchers at the Universities of Montana, Valle de México, Boise State, Universidad Veracruzana, Instituto Nacional de Pediatría and Paul-Flechsig-Institute for Brain Research heightens together with German company Analytik Jena concerns over the evolving and relentless Alzheimer’s pathology observed in young Metropolitan Mexico City (MMC) urbanites.
19 December 2018
Anniversary Year Draws to a Close
Visitors to our website are no doubt aware that JAD celebrated its 20th anniversary in 2018! Over the course of 20 years, our journal has published more papers on Alzheimer's disease (AD) than any other journal and received more citations than any other AD-focused journal. To mark this special occasion, we published an open access special anniversary issue in March.
12 November 2018
Meditation and Music May Alter Blood Markers of Cellular Aging and Alzheimer’s Disease in Adults with Early Memory Loss
A research team led by Dr. Kim Innes, a professor in the West Virginia University School of Public Health, has found that a simple meditation or music listening program may alter certain biomarkers of cellular aging and Alzheimer’s Disease in older adults who are experiencing memory loss. Study findings, reported in the Journal of Alzheimer’s Disease, also suggest these changes may be directly related to improvements in memory and cognition, sleep, mood, and quality of life.
5 November 2018
Businessman Issues Global, Multimillion Dollar Challenge for Alzheimer's Solutions
To expand the understanding and explanation of Alzheimer’s disease, United States businessman James Truchard has given a $5 million USD gift to The University of Texas at San Antonio (UTSA) College of Sciences to establish the Oskar Fischer Project. The initiative will engage the world’s brightest minds in a comprehensive literature review with the goal of synthesizing that information into one simple explanation for the cause of Alzheimer’s disease.
25 October 2018
Early Alzheimer’s Brain Pathology Linked to Psychiatric Symptoms
UC San Francisco researchers, in collaboration with the unique Brazilian Biobank for Aging Studies (BBAS) at the University of São Paulo, have shown that the earliest stages of the brain degeneration associated with Alzheimer’s disease (AD) are linked to neuropsychiatric symptoms including anxiety, depression, loss of appetite, and sleep disturbances.
22 October 2018
Long-Running Study Identifies Modifiable Dementia Risk Factor in Older Adults
For older adults, it may seem as though the die is already cast regarding their odds of developing dementia, but new research from the University of Pittsburgh has identified a dementia risk factor among older adults that should be modifiable even well into old age. The study, which draws on data collected from following hundreds of elderly Pittsburghers for more than 15 years, was published today in JAD.
19 October 2018
Hypothesis Underpinning Dementia Research ‘Flawed’
A hypothesis which has been the standard way of explaining how the body develops Alzheimer’s Disease for almost 30 years is flawed, according to a University of Manchester biologist. The ‘Amyloid Cascade’ argues that a series of stages, starting from the deposition of a starch-like protein called amyloid and ending with dementia, should be reassessed. Prof Andrew Doig’s review of 120 scientific papers finds that the stages were not linked together in a cascade and the progression to dementia was not linear.
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