Latest News

4 August 2022

Common Viruses May Be Triggering the Onset of Alzheimer’s Disease

Varicella zoster virus (VZV, yellow), which commonly causes chickenpox and shingles, activates herpes simplex virus (HSV, purple) from dormancy in neural tissue grown in vitro, which then leads to an increase in plaque deposits and decrease in neural signaling - hallmarks of Alzheimer's disease. Credit: Tufts University

Alzheimer’s disease (AD) can begin almost imperceptibly, often masquerading in the early months or years as forgetfulness that is common in older age. What causes the disease remains largely a mystery. But researchers at Tufts University and the University of Oxford, using a three-dimensional human tissue culture model mimicking the brain, have shown that varicella zoster virus, which commonly causes chickenpox and shingles, may activate herpes simplex, another common virus, to set in motion the early stages of AD.

2 August 2022

Overweight was Negatively Associated with Dementia in Women, whereas there was a Positive Underweight-Dementia Relationship in Men

Journal of Alzheimer's Disease

A substantial body of literature has analyzed the potential association between late-life body mass index (BMI) and dementia. Given that there are some data suggesting that estrogen has neuroprotective effects, it is possible that the BMI-dementia relationship differs between women and men. However, to date, no research has yet investigated this hypothesis.

1 August 2022

Gender Differences in Behaviors Linked to Faster Cognitive Decline Revealed in Research

Dr Katrin Wolfová, PhD student at Charles University in Prague

Men who experience behavior changes including apathy or having false beliefs and perceptions in later life are at risk of faster cognitive decline than women, according to new research. A study led by Charles University, in collaboration with the University of Exeter and King’s College London, looked at changes in behavior in cognitively healthy people aged 50 and older, which have previously been linked to a higher risk of developing brain problems.

27 June 2022

UTHealth Houston Study: Flu Vaccination Linked to 40% Reduced Risk of Alzheimer’s Disease

Paul E. Schulz, MD

People who received at least one influenza vaccine were 40% less likely than their non-vaccinated peers to develop Alzheimer’s disease over the course of four years, according to a new study from UTHealth Houston. Research led by first author Avram S. Bukhbinder, MD, a recent alumnus of McGovern Medical School at UTHealth Houston, and senior author Paul. E. Schulz, MD, the Rick McCord Professor in Neurology at McGovern Medical School, compared the risk of Alzheimer’s disease incidence between patients with and without prior flu vaccination in a large nationwide sample of US adults aged 65 and older.

23 June 2022

Poor Sleep and Nighttime Wakefulness Associated With Diminished Cognitive Function Among African Americans, Study Finds

Rand Corporation

More fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with lower cognitive function such as poor attention, according to a new study. Studying people over a five-year period, researchers from the RAND Corporation and the University of Pittsburgh found that those whose sleep worsened over time had poorer attention, executive function and visuospatial ability.

30 May 2022

Quantifying Cognitive Decline in Dogs Could Help Humans with Alzheimer’s Disease

Researchers have found that a suite of complementary tests can quantify changes in dogs suspected of suffering from cognitive decline. The approach could not only aid owners in managing their elderly canine’s care, but could also serve as a model for evaluating cognitive decline progression in – and treatments for – humans with Alzheimer’s disease.

1 May 2022

New JAD Board Appointments

JAD logo

We are pleased to announce new appointments to the JAD Editorial Board, which means we have an equal number of female and male representation within the senior team (i.e. looking at only the positions of Deputy Editor and Editor-in-Chief).As announced recently, the journal supports the IOS Press Diversity and Inclusion Statement and we are making changes relating to SDG 5 (gender equality) and SDG 10 (reduced inequalities) in terms of diversity.

29 April 2022

New Research Identifies Blood Biomarker for Predicting Dementia Before Symptoms Develop

Emer McGrath

New research from NUI Galway and Boston University has identified a blood biomarker that could help identify people with the earliest signs of dementia, even before the onset of symptoms. The researchers measured blood levels of P-tau181, a marker of neurodegeneration, in 52 cognitively healthy adults, from the US-based Framingham Heart Study, who later went on to have specialized brain PET scans. The blood samples were taken from people who had no cognitive symptoms and who had normal cognitive testing at the time of blood testing.


Subscribe to Latest News