Title | Risk Assessment of Alzheimer's Disease using the Information Diffusion Model from Structural Magnetic Resonance Imaging. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Beheshti, I, Olya, HGT, Demirel, H |
Corporate Authors | Alzheimer’s Disease Neuroimaging Initiative |
Journal | J Alzheimers Dis |
Volume | 52 |
Issue | 4 |
Pagination | 1335-42 |
Date Published | 2016 Apr 05 |
ISSN | 1875-8908 |
Abstract | BACKGROUND: Recently, automatic risk assessment methods have been a target for the detection of Alzheimer's disease (AD) risk. OBJECTIVE: This study aims to develop an automatic computer-aided AD diagnosis technique for risk assessment of AD using information diffusion theory. METHODS: Information diffusion is a fuzzy mathematics logic of set-value that is used for risk assessment of natural phenomena, which attaches fuzziness (uncertainty) and incompleteness. Data were obtained from voxel-based morphometry analysis of structural magnetic resonance imaging. RESULTS AND CONCLUSION: The information diffusion model results revealed that the risk of AD increases with a reduction of the normalized gray matter ratio (p > 0.5, normalized gray matter ratio |
DOI | 10.3233/JAD-151176 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 27060960 |