Title | Self-Perceived Quality of Life Among Patients with Alzheimer's Disease: Two Longitudinal Models of Analysis. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Conde-Sala, JL, Turró-Garriga, O, Portellano-Ortiz, C, Viñas-Diez, V, Gascón-Bayarri, J, Reñé-Ramírez, R |
Journal | J Alzheimers Dis |
Volume | 52 |
Issue | 3 |
Pagination | 999-1012 |
Date Published | 2016 Apr 12 |
ISSN | 1875-8908 |
Abstract | The objective was to analyze the factors that influence self-perceived quality of life (QoL) in patients with Alzheimer's disease (AD), contrasting two different longitudinal models. A total of 127 patients were followed up over 24 months. The instruments applied were: Quality of Life in Alzheimer's Disease scale (QoL-AD), Geriatric Depression Scale-15, Anosognosia Questionnaire-Dementia, Disability Assessment in Dementia, Neuropsychiatric Inventory, and the Mini-Mental State Examination. Two models for grouping patients were tested: 1) Baseline score on the QoL-AD (QoL-Baseline), and 2) Difference in QoL-AD score between baseline and follow-up (QoL-Change). Generalized estimating equations were used to analyze longitudinal data, and multinomial regression analyses were performed. Over the follow-up period the QoL-Baseline model showed greater variability between groups (Wald χ2 = 172.3, p 37 QoL-AD). The model based on baseline scores (QoL-Baseline) was better than the QoL-Change model in terms of identifying trajectories and predictors of QoL in AD. |
DOI | 10.3233/JAD-160040 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 27079721 |