Title | Chronic Traumatic Encephalopathy Presenting as Alzheimer's Disease in a Retired Soccer Player. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Grinberg, LT, Anghinah, R, Nascimento, CFernandes, Amaro, E, Leite, RP, Martin, Mda Graça, Naslavsky, MS, Takada, LT, Filho, WJacob, Pasqualucci, CA, Nitrini, R |
Journal | J Alzheimers Dis |
Volume | 54 |
Issue | 1 |
Pagination | 169-74 |
Date Published | 2016 Jul 29 |
ISSN | 1875-8908 |
Abstract | The relationship between soccer and chronic traumatic encephalopathy (CTE) is not well established. We report clinicopathological correlations in an 83-year-old retired center-back soccer player, with no history of concussion, manifesting typical Alzheimer-type dementia. Examination revealed mixed pathology including widespread CTE, moderate Alzheimer's disease, hippocampal sclerosis, and TDP-43 proteinopathy. This case adds to a few CTE cases described in soccer players. Furthermore, it corroborates that CTE may present clinically as typical Alzheimer-type dementia. Further studies investigating the extent to which soccer is a risk for CTE are needed. |
DOI | 10.3233/JAD-160312 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 27472879 |
Grant List | R01 AG040311 / AG / NIA NIH HHS / United States |