Title | EEG Markers of Dementia with Lewy Bodies: A Multicenter Cohort Study. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Bonanni, L, Franciotti, R, Nobili, F, Kramberger, MG, Taylor, J-P, Garcia-Ptacek, S, N Falasca, W, Famá, F, Cromarty, R, Onofrj, M, Aarsland, D |
Corporate Authors | E-DLB study group |
Journal | J Alzheimers Dis |
Volume | 54 |
Issue | 4 |
Pagination | 1649-1657 |
Date Published | 2016 Oct 18 |
ISSN | 1875-8908 |
Abstract | Quantitative EEG (QEEG) has demonstrated good discriminative capacity for dementia with Lewy bodies (DLB) diagnosis as compared to Alzheimer's disease (AD) with a predictive value of 100% in a single cohort study. EEG in DLB was characterized by a dominant frequency (DF) in pre-alpha (5.5-7.5 Hz), theta, or delta bands and DF variability (DFV) >1.2 Hz, frequency prevalence (FP) pre-alpha in >40% and FP alpha in 20) collected from four European Centers. EEG traces from 19 scalp derivations were acquired as at least 10 min continuous signals and epoched in off-setting as series of 2-second-long epochs, subsequently processed by Fast Fourier Transform (frequency resolution 0.5 Hz). DLB patients showed EEG specific abnormalities in posterior derivations characterized by DF 50%, FP alpha 0.5 Hz. AD patients displayed stable alpha DF, DFV 55%. DLB and AD differed for DF (p |
DOI | 10.3233/JAD-160435 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 27589528 |