Journal of Alzheimer's Disease
Published on Journal of Alzheimer's Disease (https://www.j-alz.com)

Home > EEG Markers of Dementia with Lewy Bodies: A Multicenter Cohort Study.

TitleEEG Markers of Dementia with Lewy Bodies: A Multicenter Cohort Study.
Publication TypeJournal Article
Year of Publication2016
AuthorsBonanni, L, Franciotti, R, Nobili, F, Kramberger, MG, Taylor, J-P, Garcia-Ptacek, S, N Falasca, W, Famá, F, Cromarty, R, Onofrj, M, Aarsland, D
Corporate AuthorsE-DLB study group
JournalJ Alzheimers Dis
Volume54
Issue4
Pagination1649-1657
Date Published2016 Oct 18
ISSN1875-8908
Abstract

Quantitative EEG (QEEG) has demonstrated good discriminative capacity for dementia with Lewy bodies (DLB) diagnosis as compared to Alzheimer's disease (AD) with a predictive value of 100% in a single cohort study. EEG in DLB was characterized by a dominant frequency (DF) in pre-alpha (5.5-7.5 Hz), theta, or delta bands and DF variability (DFV) >1.2 Hz, frequency prevalence (FP) pre-alpha in >40% and FP alpha in 20) collected from four European Centers. EEG traces from 19 scalp derivations were acquired as at least 10 min continuous signals and epoched in off-setting as series of 2-second-long epochs, subsequently processed by Fast Fourier Transform (frequency resolution 0.5 Hz). DLB patients showed EEG specific abnormalities in posterior derivations characterized by DF 50%, FP alpha 0.5 Hz. AD patients displayed stable alpha DF, DFV 55%. DLB and AD differed for DF (p 

DOI10.3233/JAD-160435
Alternate JournalJ. Alzheimers Dis.
PubMed ID27589528
E-mail Icon
Comment Icon
  • Comment
Bookmark Icon Bookmark Recommend Icon Recommend Follow Icon Follow
  • Comment
| Bookmark | Recommend | Follow

Source URL: https://www.j-alz.com/content/eeg-markers-dementia-lewy-bodies-multicenter-cohort-study