Journal of Alzheimer's Disease
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Home > Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study.

TitlePhysical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study.
Publication TypeJournal Article
Year of Publication2017
AuthorsFenesi, B, Fang, H, Kovacevic, A, Oremus, M, Raina, P, Heisz, JJ
JournalJ Alzheimers Dis
Volume56
Issue1
Pagination297-303
Date Published2017
ISSN1875-8908
Abstract

Genetics and lifestyle independently determine dementia risk, but the interaction is unclear. We assessed the interactive relationship of apolipoprotein E (APOE) genotype and physical exercise on dementia risk over a 5-year period in 1,646 older adults from the Canadian Study of Health and Aging who were dementia-free at baseline. Physical exercise moderated the relationship between genotype and dementia (p 

DOI10.3233/JAD-160424
Alternate JournalJ. Alzheimers Dis.
PubMed ID27911292
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