Title | Visuospatial Functioning in Cerebral Amyloid Angiopathy: A Pilot Study. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Valenti, R, Charidimou, A, Xiong, L, Boulouis, G, Fotiadis, P, Ayres, A, Riley, G, Kuijf, HJ, Reijmer, YD, Pantoni, L, M Gurol, E, Davidsdottir, S, Greenberg, SM, Viswanathan, A |
Journal | J Alzheimers Dis |
Volume | 56 |
Issue | 4 |
Pagination | 1223-1227 |
Date Published | 2017 |
ISSN | 1875-8908 |
Abstract | Cerebral amyloid angiopathy (CAA) is a contributor to cognitive impairment in the elderly. We hypothesized that the posterior cortical predilection of CAA would cause visual-processing impairment. We systematically evaluated visuospatial abilities in 22 non-demented CAA patients. Neurocognitive evaluation demonstrated visuoperceptual impairment (23% on Benton Facial Recognition Test [BFRT] and 13.6% on Benton Judgment of Line Orientation Test [BJLO]). BFRT was inversely correlated with white matter hyperintensities volume and BJLO with parietal cerebral microbleeds. This pilot study highlights the presence of visual-processing deficits in CAA. The impairment could be related to global disease severity in addition to local brain injury. |
DOI | 10.3233/JAD-160927 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 28222510 |