Title | Impact of Recruitment Methods in Subjective Cognitive Decline. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Abdelnour, C, Rodríguez-Gómez, O, Alegret, M, Valero, S, Moreno-Grau, S, Sanabria, Á, Hernandez, I, Rosende-Roca, M, Vargas, L, Mauleón, A, Sánchez, D, Espinosa, A, Ortega, G, Pérez-Cordón, A, Diego, S, Gailhajanet, A, Guitart, M, Sotolongo-Grau, O, Ruiz, A, Tárraga, L, Boada, M |
Journal | J Alzheimers Dis |
Volume | 57 |
Issue | 2 |
Pagination | 625-632 |
Date Published | 2017 |
ISSN | 1875-8908 |
Abstract | BACKGROUND: Recruitment methods can determine sample characteristics in mild cognitive impairment and Alzheimer's disease dementia, but little is known about its influence in subjective cognitive decline (SCD). OBJECTIVE: To determine the influence of two types of recruitment methods in the characteristics of individuals with SCD. METHODS: We select and compare clinical and neuropsychological features, and frequency of APOE ɛ4 allele of 326 subjects with SCD from two cohorts: Open House Initiative (OHI) versus Memory Unit (MU). A logistic regression analysis (LRA), using gender and years of education as covariates, was used to examine the neuropsychological variables. RESULTS: The OHI sample were mostly women (75.9% versus 64.5%, p CONCLUSION: SCD subjects showed different demographic and neuropsychological characteristics depending on the recruitment method, which should be taken into account in the design of research studies with this target population. |
DOI | 10.3233/JAD-160915 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 28269773 |