Title | The Distinction of Amyloid-β Protein Precursor (AβPP) Ratio in Platelet Between Alzheimer's Disease Patients and Controls: A Systematic Review and Meta-Analysis. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Shi, Y, Gu, L, Alsharif, AAzeez, Zhang, Z |
Journal | J Alzheimers Dis |
Volume | 59 |
Issue | 3 |
Pagination | 1037-1044 |
Date Published | 2017 |
ISSN | 1875-8908 |
Abstract | To systematically assess the clinical significance of platelet amyloid-β protein precursor (AβPP) ratio between Alzheimer's disease (AD) patients and controls. 14 articles were selected in this analysis by search of databases including PubMed and Web of Science up to December 2016. Random effects models were used to calculate the standardized mean difference (SMD). Subgroup analyses were used to detect the cause of heterogeneity. The result showed a significant drop in platelet AβPP ratio in AD patients compared to controls [SMD: -1.871; 95% CI: (-2.33, -1.41); p |
DOI | 10.3233/JAD-170253 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 28731441 |