Journal of Alzheimer's Disease
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Home > The Distinction of Amyloid-β Protein Precursor (AβPP) Ratio in Platelet Between Alzheimer's Disease Patients and Controls: A Systematic Review and Meta-Analysis.

TitleThe Distinction of Amyloid-β Protein Precursor (AβPP) Ratio in Platelet Between Alzheimer's Disease Patients and Controls: A Systematic Review and Meta-Analysis.
Publication TypeJournal Article
Year of Publication2017
AuthorsShi, Y, Gu, L, Alsharif, AAzeez, Zhang, Z
JournalJ Alzheimers Dis
Volume59
Issue3
Pagination1037-1044
Date Published2017
ISSN1875-8908
Abstract

To systematically assess the clinical significance of platelet amyloid-β protein precursor (AβPP) ratio between Alzheimer's disease (AD) patients and controls. 14 articles were selected in this analysis by search of databases including PubMed and Web of Science up to December 2016. Random effects models were used to calculate the standardized mean difference (SMD). Subgroup analyses were used to detect the cause of heterogeneity. The result showed a significant drop in platelet AβPP ratio in AD patients compared to controls [SMD: -1.871; 95% CI: (-2.33, -1.41); p 

DOI10.3233/JAD-170253
Alternate JournalJ. Alzheimers Dis.
PubMed ID28731441
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Source URL: https://www.j-alz.com/content/distinction-amyloid-%CE%B2-protein-precursor-a%CE%B2pp-ratio-platelet-between-alzheimers-disease