| Title | Serum Non-Ceruloplasmin Non-Albumin Copper Elevation in Mild Cognitive Impairment and Dementia due to Alzheimer's Disease: A Case Control Study. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Rozzini, L, Lanfranchi, F, Pilotto, A, Catalani, S, Gilberti, MEnrica, Paganelli, M, Apostoli, P, Padovani, A |
| Journal | J Alzheimers Dis |
| Volume | 61 |
| Issue | 3 |
| Pagination | 907-912 |
| Date Published | 2018 |
| ISSN | 1875-8908 |
| Keywords | Aged, Aged, 80 and over, Alzheimer Disease, Case-Control Studies, Cognitive Dysfunction, Copper, Female, Humans, Magnetic Resonance Imaging, Male, Psychiatric Status Rating Scales |
| Abstract | Several studies showed high serum copper levels in Alzheimer's disease (AD). The present study applied a newly developed method to detect serum copper free from proteins (free-Cu). Forty-four patients affected by dementia due to AD, thirty-six patients affected by mild cognitive impairment (MCI) due to AD, and twenty-eight healthy controls underwent clinical, cognitive, and MRI assessment. The new method showed higher free-Cu concentrations in MCI and dementia due to AD compared to controls (p |
| DOI | 10.3233/JAD-170552 |
| Alternate Journal | J. Alzheimers Dis. |
| PubMed ID | 29332043 |
