| Title | Validation of the Delayed Matching-to-Sample Task 48 (DMS48) in Elderly Chinese. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Feng, X, Zhou, A, Liu, Z, Li, F, Wei, C, Zhang, G, Jia, J |
| Journal | J Alzheimers Dis |
| Volume | 61 |
| Issue | 4 |
| Pagination | 1611-1618 |
| Date Published | 2018 |
| ISSN | 1875-8908 |
| Keywords | Aged, Aged, 80 and over, Alzheimer Disease, China, Cognitive Dysfunction, Cross-Sectional Studies, Female, Humans, Linear Models, Male, Memory Disorders, Middle Aged, Neuropsychological Tests, ROC Curve, Sensitivity and Specificity, Severity of Illness Index |
| Abstract | BACKGROUND: Delayed Matching-to-Sample Task 48 (DMS48), a brief tool measuring visual recognition memory, is valid to identify the early stage of Alzheimer's disease (AD) in Caucasians. However, little data is available in Chinese. OBJECTIVE: To develop norms and optimal cutoff points for the DMS48 in Chinese elders. METHODS: A cross-sectional study was conducted in seven memory clinics from five cities across China. DMS48 was applied to 369 Chinese aged 50 or older (138 cognitively normal [CN], 112 mild cognitive impairment due to AD (MCI-A), and 119 mild AD dementia). The demographic factors which influence DMS48 scores were investigated and the norms were established considering those factors. Receiver operating characteristic (ROC) analysis was used to determine the optimal cutoff points. RESULTS: Age was shown to influence DMS48 scores (r = -0.36, p  CONCLUSION: This study proved that DMS48 is of good validation in screening MCI-A in elderly Chinese. |
| DOI | 10.3233/JAD-170530 |
| Alternate Journal | J. Alzheimers Dis. |
| PubMed ID | 29376851 |
