| Title | Executive Dysfunction Detected with the Frontal Assessment Battery in Alzheimer's Disease Versus Vascular Dementia. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | D'Onofrio, G, Panza, F, Sancarlo, D, Addante, F, Solfrizzi, V, Cantarini, C, Mangiacotti, A, Lauriola, M, Cascavilla, L, Paris, F, Lozupone, M, Daniele, A, Greco, A, Seripa, D |
| Journal | J Alzheimers Dis |
| Volume | 62 |
| Issue | 2 |
| Pagination | 699-711 |
| Date Published | 2018 |
| ISSN | 1875-8908 |
| Keywords | Aged, Aged, 80 and over, Alzheimer Disease, Cognitive Dysfunction, Comorbidity, Dementia, Vascular, Executive Function, Female, Frontal Lobe, Geriatric Assessment, Humans, Logistic Models, Male, Polypharmacy, Severity of Illness Index |
| Abstract | Alzheimer's disease (AD) and vascular dementia (VaD) lead to progressive decline in executive function. We estimated the prevalence of executive dysfunction in AD and VaD patients, investigating cognitive, functional, and clinical correlates and also using a multidimensional approach based on a standardized comprehensive geriatric assessment (CGA). We included 215 patients (115 AD patients and 100 VaD patients) consecutively evaluated with a complete cognitive and affective assessment, a CGA, and the Frontal Assessment Battery (FAB) with six subtests investigating conceptualization, mental flexibility, motor programming, sensitivity to interference, inhibitory control, and environmental autonomy. The prevalence of dysexecutive syndrome screened with a FAB score |
| DOI | 10.3233/JAD-170365 |
| Alternate Journal | J. Alzheimers Dis. |
| PubMed ID | 29480171 |
