| Title | PCSK9 Concentrations in Cerebrospinal Fluid Are Not Specifically Increased in Alzheimer's Disease. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Courtemanche, H, Bigot, E, Pichelin, M, Guyomarch, B, Boutoleau-Bretonnière, C, Le May, C, Derkinderen, P, Cariou, B |
| Journal | J Alzheimers Dis |
| Volume | 62 |
| Issue | 4 |
| Pagination | 1519-1525 |
| Date Published | 2018 |
| ISSN | 1875-8908 |
| Abstract | The role of PCSK9 in Alzheimer's disease (AD) is controversial. We compared cerebrospinal fluid (CSF) PCSK9 concentrations in 36 AD and 31 non-AD patients. CSF PCSK9 levels did not differ between AD and non-AD groups (2.80 versus 2.62 ng/mL). However, PCSK9 CSF levels were increased in AD and non-AD patients with other neurodegenerative process (non-AD ND, n = 20) compared to patients without neurodegenerative disorders (non-ND, n = 11): 2.80 versus 2.30 (p |
| DOI | 10.3233/JAD-170993 |
| Alternate Journal | J. Alzheimers Dis. |
| PubMed ID | 29562508 |
