Title | Severity-Related Increase and Cognitive Correlates of Serum VEGF Levels in Alzheimer's Disease ApoE4 Carriers. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | X Alvarez, A, Alvarez, I, Aleixandre, M, Linares, C, Muresanu, D, Winter, S, Moessler, H |
Journal | J Alzheimers Dis |
Volume | 63 |
Issue | 3 |
Pagination | 1003-1013 |
Date Published | 2018 |
ISSN | 1875-8908 |
Abstract | Vascular endothelial growth factor (VEGF) is an angioneurin involved in the regulation of vascular and neural functions relevant for the pathophysiology of Alzheimer's disease (AD), but the influence of AD severity and ApoE4 status on circulating VEGF and its relationship with cognition has not been investigated. We assessed serum VEGF levels and cognitive performance in AD, amnestic mild cognitive impairment (MCI), and control subjects. VEGF levels were higher in AD patients than in MCI cases and controls (p |
DOI | 10.3233/JAD-160477 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 29710700 |