| Title | Combination Therapy of Serotonin Reuptake Inhibitors and Memantine for Obsessive- Compulsive Disorder: A Meta-Analysis of Double-Blind, Randomized, Placebo-Controlled Trials. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Kishi, T, Matsuda, Y, Iwata, N |
| Journal | J Alzheimers Dis |
| Volume | 64 |
| Issue | 1 |
| Pagination | 43-48 |
| Date Published | 2018 |
| ISSN | 1875-8908 |
| Abstract | We performed a meta-analysis to determine whether combination therapy with serotonin reuptake inhibitors (SRIs) and memantine (MEM) was beneficial for the treatment of obsessive- compulsive disorder. This study included three double-blind, randomized, placebo-controlled trials. MEM+SRI was superior to placebo+SRI with regard to response rate [primary outcome, n = 97; risk ratio = 0.22; 95% confidence intervals (CI) = 0.12-0.42; p |
| DOI | 10.3233/JAD-180237 |
| Alternate Journal | J. Alzheimers Dis. |
| PubMed ID | 29865079 |
