| Title | Interactive Effect of Depression and Cognitive Impairment on Olfactory Identification in Elderly People. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Chen, B, Zhong, X, Mai, N, Peng, Q, Zhang, M, Chen, X, Wu, Z, Zou, L, Liang, W, Ouyang, C, Wu, Y, Ning, Y |
| Journal | J Alzheimers Dis |
| Volume | 66 |
| Issue | 4 |
| Pagination | 1645-1655 |
| Date Published | 2018 |
| ISSN | 1875-8908 |
| Abstract | Olfactory identification (OI) deficits have been regarded as an indicator of cognitive impairment in the elderly, but few studies have analyzed the mixed effect of depression on OI. Since depression is common in the elderly and strongly associated with OI, we aimed to explore whether the comorbidity of depression and cognitive impairment may be associated with worse outcomes. In total, 153 elderly patients with depression and 154 normal elderly were recruited. Subjects underwent assessments of depression, cognitive function, and OI. Information on the factors that may affect OI performance was collected (age, sex, smoking history, diabetes, etc.). Correlation analysis showed that several factors had a significant influence on OI performance in the elderly, including severity of depression, cognitive scores, age, sex, and years of education (p |
| DOI | 10.3233/JAD-180760 |
| Alternate Journal | J. Alzheimers Dis. |
| PubMed ID | 30475771 |
