Title | Patterns of Physical Activity and Sedentary Behavior for Older Adults with Alzheimer's Disease, Mild Cognitive Impairment, and Cognitively Normal in Hong Kong. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Lu, Z, Harris, TB, Shiroma, EJ, Leung, J, Kwok, T |
Journal | J Alzheimers Dis |
Volume | 66 |
Issue | 4 |
Pagination | 1453-1462 |
Date Published | 2018 |
ISSN | 1875-8908 |
Abstract | BACKGROUND: Alzheimer's disease (AD) is the most common form of dementia, and mild cognitive impairment (MCI) is a transitional phase between healthy cognition and dementia. Physical activity (PA) has protective effects on cognitive decline. However, few studies have examined how PA and sedentary behavior is structured throughout the day in older adults across varied cognitive status in Hong Kong. OBJECTIVE: This study aimed to compare patterns of PA and sedentary behavior among individuals with AD, MCI, or normal cognition living in Hong Kong. METHODS: Participants in the MrOs and MsOs Hong Kong cohort study and the Hong Kong AD biomarker study (nā=ā810) wore a wrist-worn accelerometer for 7 days in free-living environment. Patterns of PA in wake time and in-bed time, and detailed analysis of sedentary bouts were compared between groups using analysis of covariance adjusting for covariates. RESULTS: Participants with MCI and low MoCA only did not differ from their cognitively normal peers in PA and sedentary behavior. Nevertheless, when comparing to the others, participants with AD exhibited significantly lower average daily counts per minute during the day (pā CONCLUSIONS: The pattern of PA and sedentary behavior was different between individuals with AD and the others. Cognitive status may alter the purpose and type of PA intervention for AD individuals. |
DOI | 10.3233/JAD-180805 |
Alternate Journal | J. Alzheimers Dis. |
PubMed ID | 30412502 |
PubMed Central ID | PMC6301091 |
Grant List | Z99 AG999999 / NULL / Intramural NIH HHS / United States ZIA AG006020-11 / NULL / Intramural NIH HHS / United States |