The 2016 Alzheimer Award goes to Mark Bondi for "Subtle Cognitive Decline and Biomarker Staging in Preclinical Alzheimer's Disease." For more information, click here or go to http://www.j-alz.com/award.
The Journal of Alzheimer's Disease
is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease.
We applied bibliometric analytics to identify 300 highly cited papers relevant to AD research, published in the last 5 years. Members voted for their top 10 most influential papers. See the results!
LATEST JAD EDITORS’ BLOG Is sporadic Alzheimer’s disease a form of diabetes? by Paula Moreira, PhD
The Alzheimer’s Funding Analyzer (AFA) showcases funding distribution from 42 countries and allows the end-user to conduct line-of-investigation queries to look for funding trends.
Neurovascular trophic coupling change with an increase of inner diameter of parenchymal vessels, morphological change of vascular endothelial cells, and a decreased BDNG expression in endothelia in APP23+CCH (chronic cerebral hypoperfusion) model. From Shang et al., JAD52(1)
Amyloid plaques in Tg2576 mice, stained by 4G8 antibody (G1), are associated with nanoparticles containing ICG dye (G2) and ET6-21 ligand (G3); G4 shows overlay. Higher magnification (60X) (H1H4) shows colocalization of nanoparticles within single plaque. From Tanifum et al., JAD 52(2).
Positive striatal [18F]flutemetamol PET signal (right panel), with MR images for orientation (left panel). Arrows indicate position of striatum (head of caudate nucleus and putamen). From Beach et al., JAD52(3).
Predicted structures of the human presenilin 1 protein and the orthologous presenilin B protein from the social amoeba Dictyostelium discoideum suggests conserved function. From Otto, Sharma, and Williams, JAD52(4).
Intraneural accumulation of amylin (green) increases synthesis of IL-1β (red) in brains of patients with Alzheimer’s disease and Type-2 diabetes (AD-T2D). Scale bars, 20 μm. From Verma et al., JAD53(1)
Physical exercise increases hippocampal neurogenesis in the TgCRND8 mouse model of amyloidosis. The merged images show colocalization of BrdU/NeuN markers (arrow) and BrdU/GFAP markers (arrowhead). Scale bar: 50 μm. From Maliszewska-Cyna et al., JAD53(1).
In the delayed-match-to-sample task, mild cognitive impairment patients (MCI) showed reduced repetition-driven suppression in the occipital brain regions relative to normal controls (NC). Activation is in red and deactivation is in blue. From Yu et al., JAD53(2).
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