Acetamides
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Adult
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Aged
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Alleles
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Alzheimer Disease
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Amyloid beta-Peptides
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Animals
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Apolipoprotein E4
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Biomarkers
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Blotting, Western
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Brain
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Cells, Cultured
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Cerebral Cortex
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Dendritic Spines
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Female
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Gene Knockdown Techniques
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Genotype
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Green Fluorescent Proteins
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Hippocampus
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Histone Deacetylase Inhibitors
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Humans
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
Immunohistochemistry
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Male
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M.,
“Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.”,
Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
MAP Kinase Signaling System
J. Min Song, Sung, Y. Me, Nam, J. Han, Yoon, H., Chung, A., Moffat, E., Jung, M., Pak, D. T. S., Kim, J., and Hoe, H. - S.,
“A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.”,
J Alzheimers Dis, vol. 51, no. 2, pp. 591-604, 2016.
Pages