Translational Medical Research
H. Hampel, Toschi, N., Babiloni, C., Baldacci, F., Black, K. L., Bokde, A. L. W., Bun, R. S., Cacciola, F., Cavedo, E., Chiesa, P. A., Colliot, O., Coman, C. - M., Dubois, B., Duggento, A., Durrleman, S., Ferretti, M. - T., George, N., Genthon, R., Habert, M. - O., Herholz, K., Koronyo, Y., Koronyo-Hamaoui, M., Lamari, F., Langevin, T., Lehéricy, S., Lorenceau, J., Neri, C., Nisticò, R., Nyasse-Messene, F., Ritchie, C., Rossi, S., Santarnecchi, E., Sporns, O., Verdooner, S. R., Vergallo, A., Villain, N., Younesi, E., Garaci, F., and Lista, S.,
“Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology.”,
J Alzheimers Dis, vol. 64, no. s1, pp. S47-S105, 2018.
Time Factors
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
tau Proteins
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M.,
“The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
Systems Biology
H. Hampel, Toschi, N., Babiloni, C., Baldacci, F., Black, K. L., Bokde, A. L. W., Bun, R. S., Cacciola, F., Cavedo, E., Chiesa, P. A., Colliot, O., Coman, C. - M., Dubois, B., Duggento, A., Durrleman, S., Ferretti, M. - T., George, N., Genthon, R., Habert, M. - O., Herholz, K., Koronyo, Y., Koronyo-Hamaoui, M., Lamari, F., Langevin, T., Lehéricy, S., Lorenceau, J., Neri, C., Nisticò, R., Nyasse-Messene, F., Ritchie, C., Rossi, S., Santarnecchi, E., Sporns, O., Verdooner, S. R., Vergallo, A., Villain, N., Younesi, E., Garaci, F., and Lista, S.,
“Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology.”,
J Alzheimers Dis, vol. 64, no. s1, pp. S47-S105, 2018.
Societies, Medical
B. Dubois, Feldman, H. H., Jacova, C., Hampel, H., Molinuevo, J. Luis, Blennow, K., DeKosky, S. T., Gauthier, S., Selkoe, D., Bateman, R., Cappa, S., Crutch, S., Engelborghs, S., Frisoni, G. B., Fox, N. C., Galasko, D., Habert, M. - O., Jicha, G. A., Nordberg, A., Pasquier, F., Rabinovici, G., Robert, P., Rowe, C., Salloway, S., Sarazin, M., Epelbaum, S., de Souza, L. C., Vellas, B., Visser, P. J., Schneider, L., Stern, Y., Scheltens, P., and Cummings, J. L.,
“Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria.”,
Lancet Neurol, vol. 13, no. 6, pp. 614-29, 2014.
Sensitivity and Specificity
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
ROC Curve
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
Risk
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
Retrospective Studies
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M.,
“The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
Reproducibility of Results
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
Prognosis
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
Predictive Value of Tests
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M.,
“The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
Precision Medicine
H. Hampel, Toschi, N., Babiloni, C., Baldacci, F., Black, K. L., Bokde, A. L. W., Bun, R. S., Cacciola, F., Cavedo, E., Chiesa, P. A., Colliot, O., Coman, C. - M., Dubois, B., Duggento, A., Durrleman, S., Ferretti, M. - T., George, N., Genthon, R., Habert, M. - O., Herholz, K., Koronyo, Y., Koronyo-Hamaoui, M., Lamari, F., Langevin, T., Lehéricy, S., Lorenceau, J., Neri, C., Nisticò, R., Nyasse-Messene, F., Ritchie, C., Rossi, S., Santarnecchi, E., Sporns, O., Verdooner, S. R., Vergallo, A., Villain, N., Younesi, E., Garaci, F., and Lista, S.,
“Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology.”,
J Alzheimers Dis, vol. 64, no. s1, pp. S47-S105, 2018.
Practice Guidelines as Topic
B. Dubois, Feldman, H. H., Jacova, C., Hampel, H., Molinuevo, J. Luis, Blennow, K., DeKosky, S. T., Gauthier, S., Selkoe, D., Bateman, R., Cappa, S., Crutch, S., Engelborghs, S., Frisoni, G. B., Fox, N. C., Galasko, D., Habert, M. - O., Jicha, G. A., Nordberg, A., Pasquier, F., Rabinovici, G., Robert, P., Rowe, C., Salloway, S., Sarazin, M., Epelbaum, S., de Souza, L. C., Vellas, B., Visser, P. J., Schneider, L., Stern, Y., Scheltens, P., and Cummings, J. L.,
“Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria.”,
Lancet Neurol, vol. 13, no. 6, pp. 614-29, 2014.
Polymorphism, Single Nucleotide
L. Jones, Holmans, P. A., Hamshere, M. L., Harold, D., Moskvina, V., Ivanov, D., Pocklington, A., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Pahwa, J. Singh, Jones, N., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., A Smith, D., Love, S., Kehoe, P. G., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schürmann, B., Heun, R., Kölsch, H., van den Bussche, H., Heuser, I., Peters, O., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. - H., Klopp, N., Wichmann, H. - E., Rüther, E., Carrasquillo, M. M., V Pankratz, S., Younkin, S. G., Hardy, J., O'Donovan, M. C., Owen, M. J., and Williams, J.,
“Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.”,
PLoS One, vol. 5, no. 11, p. e13950, 2010.
Phenotype
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M.,
“The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
B. Dubois, Feldman, H. H., Jacova, C., Hampel, H., Molinuevo, J. Luis, Blennow, K., DeKosky, S. T., Gauthier, S., Selkoe, D., Bateman, R., Cappa, S., Crutch, S., Engelborghs, S., Frisoni, G. B., Fox, N. C., Galasko, D., Habert, M. - O., Jicha, G. A., Nordberg, A., Pasquier, F., Rabinovici, G., Robert, P., Rowe, C., Salloway, S., Sarazin, M., Epelbaum, S., de Souza, L. C., Vellas, B., Visser, P. J., Schneider, L., Stern, Y., Scheltens, P., and Cummings, J. L.,
“Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria.”,
Lancet Neurol, vol. 13, no. 6, pp. 614-29, 2014.
Peptide Fragments
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M.,
“The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
Pattern Recognition, Automated
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
Organ Size
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
Neuropsychological Tests
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M.,
“The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
P. Suppa, Hampel, H., Kepp, T., Lange, C., Spies, L., Fiebach, J. B., Dubois, B., and Buchert, R.,
“Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 51, no. 3, pp. 867-73, 2016.
Neurophysiology
H. Hampel, Toschi, N., Babiloni, C., Baldacci, F., Black, K. L., Bokde, A. L. W., Bun, R. S., Cacciola, F., Cavedo, E., Chiesa, P. A., Colliot, O., Coman, C. - M., Dubois, B., Duggento, A., Durrleman, S., Ferretti, M. - T., George, N., Genthon, R., Habert, M. - O., Herholz, K., Koronyo, Y., Koronyo-Hamaoui, M., Lamari, F., Langevin, T., Lehéricy, S., Lorenceau, J., Neri, C., Nisticò, R., Nyasse-Messene, F., Ritchie, C., Rossi, S., Santarnecchi, E., Sporns, O., Verdooner, S. R., Vergallo, A., Villain, N., Younesi, E., Garaci, F., and Lista, S.,
“Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology.”,
J Alzheimers Dis, vol. 64, no. s1, pp. S47-S105, 2018.
Neurology
H. Hampel, Toschi, N., Babiloni, C., Baldacci, F., Black, K. L., Bokde, A. L. W., Bun, R. S., Cacciola, F., Cavedo, E., Chiesa, P. A., Colliot, O., Coman, C. - M., Dubois, B., Duggento, A., Durrleman, S., Ferretti, M. - T., George, N., Genthon, R., Habert, M. - O., Herholz, K., Koronyo, Y., Koronyo-Hamaoui, M., Lamari, F., Langevin, T., Lehéricy, S., Lorenceau, J., Neri, C., Nisticò, R., Nyasse-Messene, F., Ritchie, C., Rossi, S., Santarnecchi, E., Sporns, O., Verdooner, S. R., Vergallo, A., Villain, N., Younesi, E., Garaci, F., and Lista, S.,
“Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology.”,
J Alzheimers Dis, vol. 64, no. s1, pp. S47-S105, 2018.
Middle Aged
A. Koppara, Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Frölich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F. M., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H. - J., Schröder, J., Pantel, J., Rienhoff, O., Rüther, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J., and Wagner, M.,
“The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.”,
J Alzheimers Dis, vol. 49, no. 2, pp. 547-60, 2016.
Pages