Biblio

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2011
M. T. Fodero-Tavoletti, Okamura, N., Furumoto, S., Mulligan, R. S., Connor, A. R., McLean, C. A., Cao, D., Rigopoulos, A., Cartwright, G. A., O'Keefe, G., Gong, S., Adlard, P. A., Barnham, K. J., Rowe, C. C., Masters, C. L., Kudo, Y., Cappai, R., Yanai, K., and Villemagne, V. L., 18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease., Brain, vol. 134, no. Pt 4, pp. 1089-100, 2011.
T. E. Golde, Schneider, L. S., and Koo, E. H., Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shift., Neuron, vol. 69, no. 2, pp. 203-13, 2011.
M. A. Burguillos, Deierborg, T., Kavanagh, E., Persson, A., Hajji, N., Garcia-Quintanilla, A., Cano, J., Brundin, P., Englund, E., Venero, J. L., and Joseph, B., Caspase signalling controls microglia activation and neurotoxicity., Nature, vol. 472, no. 7343, pp. 319-24, 2011.
G. M. McKhann, Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., Mohs, R. C., Morris, J. C., Rossor, M. N., Scheltens, P., Carrillo, M. C., Thies, B., Weintraub, S., and Phelps, C. H., The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease., Alzheimers Dement, vol. 7, no. 3, pp. 263-9, 2011.
M. S. Albert, DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., Gamst, A., Holtzman, D. M., Jagust, W. J., Petersen, R. C., Snyder, P. J., Carrillo, M. C., Thies, B., and Phelps, C. H., The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease., Alzheimers Dement, vol. 7, no. 3, pp. 270-9, 2011.
L. Qiang, Fujita, R., Yamashita, T., Angulo, S., Rhinn, H., Rhee, D., Doege, C., Chau, L., Aubry, L., Vanti, W. B., Moreno, H., and Abeliovich, A., Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons., Cell, vol. 146, no. 3, pp. 359-71, 2011.
D. Kapogiannis and Mattson, M. P., Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease., Lancet Neurol, vol. 10, no. 2, pp. 187-98, 2011.
C. R. Jack, Vemuri, P., Wiste, H. J., Weigand, S. D., Aisen, P. S., Trojanowski, J. Q., Shaw, L. M., Bernstein, M. A., Petersen, R. C., Weiner, M. W., and Knopman, D. S., Evidence for ordering of Alzheimer disease biomarkers., Arch Neurol, vol. 68, no. 12, pp. 1526-35, 2011.
J. M. Castellano, Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M., Human apoE isoforms differentially regulate brain amyloid-β peptide clearance., Sci Transl Med, vol. 3, no. 89, p. 89ra57, 2011.
A. W. Bero, Yan, P., Roh, J. Hoon, Cirrito, J. R., Stewart, F. R., Raichle, M. E., Lee, J. - M., and Holtzman, D. M., Neuronal activity regulates the regional vulnerability to amyloid-β deposition., Nat Neurosci, vol. 14, no. 6, pp. 750-6, 2011.
M. Jucker and Walker, L. C., Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders., Ann Neurol, vol. 70, no. 4, pp. 532-40, 2011.
P. S. Aisen, Andrieu, S., Sampaio, C., Carrillo, M., Khachaturian, Z. S., Dubois, B., Feldman, H. H., Petersen, R. C., Siemers, E., Doody, R. S., Hendrix, S. B., Grundman, M., Schneider, L. S., Schindler, R. J., Salmon, E., Potter, W. Z., Thomas, R. G., Salmon, D., Donohue, M., Bednar, M. M., Touchon, J., and Vellas, B., Report of the task force on designing clinical trials in early (predementia) AD., Neurology, vol. 76, no. 3, pp. 280-6, 2011.
M. Jin, Shepardson, N., Yang, T., Chen, G., Walsh, D., and Selkoe, D. J., Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration., Proc Natl Acad Sci U S A, vol. 108, no. 14, pp. 5819-24, 2011.
H. Braak, Thal, D. R., Ghebremedhin, E., and Del Tredici, K., Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years., J Neuropathol Exp Neurol, vol. 70, no. 11, pp. 960-9, 2011.
R. A. Sperling, Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., Park, D. C., Reiman, E. M., Rowe, C. C., Siemers, E., Stern, Y., Yaffe, K., Carrillo, M. C., Thies, B., Morrison-Bogorad, M., Wagster, M. V., and Phelps, C. H., Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease., Alzheimers Dement, vol. 7, no. 3, pp. 280-92, 2011.
J. Li, Wang, Y. J., Zhang, M., Xu, Z. Q., Gao, C. Y., Fang, C. Q., Yan, J. C., and Zhou, H. D., Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease., Neurology, vol. 76, no. 17, pp. 1485-91, 2011.
2010
R. C. Petersen, Aisen, P. S., Beckett, L. A., Donohue, M. C., Gamst, A. C., Harvey, D. J., Jack, C. R., Jagust, W. J., Shaw, L. M., Toga, A. W., Trojanowski, J. Q., and Weiner, M. W., Alzheimer's Disease Neuroimaging Initiative (ADNI): clinical characterization., Neurology, vol. 74, no. 3, pp. 201-9, 2010.
J. C. Morris, Roe, C. M., Xiong, C., Fagan, A. M., Goate, A. M., Holtzman, D. M., and Mintun, M. A., APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging., Ann Neurol, vol. 67, no. 1, pp. 122-31, 2010.
J. A. Miller, Horvath, S., and Geschwind, D. H., Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways., Proc Natl Acad Sci U S A, vol. 107, no. 28, pp. 12698-703, 2010.
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P., Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease., Nature, vol. 467, no. 7311, pp. 95-8, 2010.
L. Jones, Holmans, P. A., Hamshere, M. L., Harold, D., Moskvina, V., Ivanov, D., Pocklington, A., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Pahwa, J. Singh, Jones, N., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., A Smith, D., Love, S., Kehoe, P. G., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schürmann, B., Heun, R., Kölsch, H., van den Bussche, H., Heuser, I., Peters, O., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. - H., Klopp, N., Wichmann, H. - E., Rüther, E., Carrasquillo, M. M., V Pankratz, S., Younkin, S. G., Hardy, J., O'Donovan, M. C., Owen, M. J., and Williams, J., Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease., PLoS One, vol. 5, no. 11, p. e13950, 2010.
D. A. Gimbel, Nygaard, H. B., Coffey, E. E., Gunther, E. C., Laurén, J., Gimbel, Z. A., and Strittmatter, S. M., Memory impairment in transgenic Alzheimer mice requires cellular prion protein., J Neurosci, vol. 30, no. 18, pp. 6367-74, 2010.
M. L. Daviglus, Bell, C. C., Berrettini, W., Bowen, P. E., E Connolly, S., Cox, N. Jean, Dunbar-Jacob, J. M., Granieri, E. C., Hunt, G., McGarry, K., Patel, D., Potosky, A. L., Sanders-Bush, E., Silberberg, D., and Trevisan, M., National Institutes of Health State-of-the-Science Conference statement: preventing alzheimer disease and cognitive decline., Ann Intern Med, vol. 153, no. 3, pp. 176-81, 2010.
E. G. McGeer and McGeer, P. L., Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy., J Alzheimers Dis, vol. 19, no. 1, pp. 355-61, 2010.
K. Iqbal, Liu, F., Gong, C. - X., and Grundke-Iqbal, I., Tau in Alzheimer disease and related tauopathies., Curr Alzheimer Res, vol. 7, no. 8, pp. 656-64, 2010.

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