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Cell Line
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P., “Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.”, Nature, vol. 467, no. 7311, pp. 95-8, 2010.
S. A. Villeda, Plambeck, K. E., Middeldorp, J., Castellano, J. M., Mosher, K. I., Luo, J., Smith, L. K., Bieri, G., Lin, K., Berdnik, D., Wabl, R., Udeochu, J., Wheatley, E. G., Zou, B., Simmons, D. A., Xie, X. S., Longo, F. M., and Wyss-Coray, T., “Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.”, Nat Med, vol. 20, no. 6, pp. 659-63, 2014.
J. Geng, Xia, L., Li, W., Zhao, C., and Dou, F., “Cycloheximide Treatment Causes a ZVAD-Sensitive Protease-Dependent Cleavage of Human Tau in Drosophila Cells.”, J Alzheimers Dis, vol. 49, no. 4, pp. 1161-8, 2016.
C. Stockburger, Miano, D., Baeumlisberger, M., Pallas, T., Arrey, T. N., Karas, M., Friedland, K., and Müller, W. E., “A Mitochondrial Role of SV2a Protein in Aging and Alzheimer's Disease: Studies with Levetiracetam.”, J Alzheimers Dis, vol. 50, no. 1, pp. 201-15, 2016.
C. -cui Yang, Kuai, X. -xian, bin Gao, W. -, Yu, J. -chun, Wang, Q., Li, L., and Zhang, L., “Morroniside-Induced PP2A Activation Antagonizes Tau Hyperphosphorylation in a Cellular Model of Neurodegeneration.”, J Alzheimers Dis, vol. 51, no. 1, pp. 33-44, 2016.
Y. Kim, Kim, C., Jang, H. Young, and Mook-Jung, I., “Inhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation.”, J Alzheimers Dis, vol. 51, no. 4, pp. 1057-68, 2016.
R. Raha-Chowdhury, Henderson, J. W., Raha, A. Alexander, Stott, S. R. W., Vuono, R., Foscarin, S., Wilson, L., Annus, T., Fincham, R., Allinson, K., Devalia, V., Friedland, R. P., Holland, A., and Zaman, S. H., “Erythromyeloid-Derived TREM2: A Major Determinant of Alzheimer's Disease Pathology in Down Syndrome.”, J Alzheimers Dis, vol. 61, no. 3, pp. 1143-1162, 2018.
K. Metsla, Kirss, S., Laks, K., Sildnik, G., Palgi, M., Palumaa, T., Tõugu, V., and Palumaa, P., “α-Lipoic Acid Has the Potential to Normalize Copper Metabolism, Which Is Dysregulated in Alzheimer's Disease.”, J Alzheimers Dis, vol. 85, no. 2, pp. 715-728, 2022.
Cell Line, Transformed
E. C. Pinnock, Jovanovic, K., Pinto, M. G., Ferreira, E., Dias, B. Da Costa, Penny, C., Knackmuss, S., Reusch, U., Little, M., Schatzl, H. M., and Weiss, S. F. T., “LRP/LR Antibody Mediated Rescuing of Amyloid-β-Induced Cytotoxicity is Dependent on PrPc in Alzheimer's Disease.”, J Alzheimers Dis, vol. 49, no. 3, pp. 645-57, 2016.
D. Chu, Tan, J., Xie, S., Jin, N., Yin, X., Gong, C. - X., Iqbal, K., and Liu, F., “GSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner.”, J Alzheimers Dis, vol. 49, no. 2, pp. 365-75, 2016.
S. Shi, Liang, D., Bao, M., Xie, Y., Xu, W., Wang, L., Wang, Z., and Qiao, Z., “Gx-50 Inhibits Neuroinflammation via α7 nAChR Activation of the JAK2/STAT3 and PI3K/AKT Pathways.”, J Alzheimers Dis, vol. 50, no. 3, pp. 859-71, 2016.
Cell Line, Tumor
A. Ezra, Rabinovich-Nikitin, I., Rabinovich-Toidman, P., and Solomon, B., “Multifunctional Effect of Human Serum Albumin Reduces Alzheimer's Disease Related Pathologies in the 3xTg Mouse Model.”, J Alzheimers Dis, vol. 50, no. 1, pp. 175-88, 2016.
K. Bourgade, Le Page, A., Bocti, C., Witkowski, J. M., Dupuis, G., Frost, E. H., and Fülöp, T., “Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model.”, J Alzheimers Dis, vol. 50, no. 4, pp. 1227-41, 2016.
M. Xie, Han, Y., Yu, Q., Wang, X., Wang, S., and Liao, X., “UCH-L1 Inhibition Decreases the Microtubule-Binding Function of Tau Protein.”, J Alzheimers Dis, vol. 49, no. 2, pp. 353-63, 2016.
A. Maes, Anthonissen, R., Wambacq, S., Simons, K., and Verschaeve, L., “The Cytome Assay as a Tool to Investigate the Possible Association Between Exposure to Extremely Low Frequency Magnetic Fields and an Increased Risk for Alzheimer's Disease.”, J Alzheimers Dis, vol. 50, no. 3, pp. 741-9, 2016.
M. Zhu, Huang, C., Ma, X., Wu, R., Zhu, W., Li, X., Liang, Z., Deng, F., Zhu, J., Xie, W., Yang, X., Jiang, Y., Wang, S., Wu, J., Geng, S., Xie, C., and Zhong, C., “Modulation of miR-19 in Aluminum-Induced Neural Cell Apoptosis.”, J Alzheimers Dis, vol. 50, no. 4, pp. 1149-62, 2016.
T. Porter, Bharadwaj, P., Groth, D., Paxman, A., Laws, S. M., Martins, R. N., and Verdile, G., “The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity.”, J Alzheimers Dis, vol. 50, no. 3, pp. 895-905, 2016.
A. K. Tripathi and Singh, N., “Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease.”, J Alzheimers Dis, vol. 51, no. 1, pp. 107-21, 2016.
H. - H. Li, Lin, S. - L., Huang, C. - N., Lu, F. - J., Chiu, P. - Y., Huang, W. - N., Lai, T. - J., and Lin, C. - L., “miR-302 Attenuates Amyloid-β-Induced Neurotoxicity through Activation of Akt Signaling.”, J Alzheimers Dis, vol. 50, no. 4, pp. 1083-98, 2016.
N. E. Gray, Zweig, J. A., Kawamoto, C., Quinn, J. F., and Copenhaver, P. F., “STX, a Novel Membrane Estrogen Receptor Ligand, Protects Against Amyloid-β Toxicity.”, J Alzheimers Dis, vol. 51, no. 2, pp. 391-403, 2016.
A. Belkacemi and Ramassamy, C., “Anthocyanins Protect SK-N-SH Cells Against Acrolein-Induced Toxicity by Preserving the Cellular Redox State.”, J Alzheimers Dis, vol. 50, no. 4, pp. 981-98, 2016.
S. Min Son, Shin, H. - J., Byun, J., Kook, S. Young, Moon, M., Chang, Y. Jin, and Mook-Jung, I., “Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation.”, J Alzheimers Dis, vol. 51, no. 4, pp. 1197-208, 2016.
G. Marwarha, Rostad, S., Lilek, J., Kleinjan, M., Schommer, J., and Ghribi, O., “Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.”, J Alzheimers Dis, vol. 57, no. 3, pp. 907-925, 2017.
P. R. Manzine, Pelucchi, S., Horst, M. A., Vale, F. A. C., Pavarini, S. C. I., Audano, M., Mitro, N., Di Luca, M., Marcello, E., and Cominetti, M. R., “microRNA 221 Targets ADAM10 mRNA and is Downregulated in Alzheimer's Disease.”, J Alzheimers Dis, vol. 61, no. 1, pp. 113-123, 2018.
J. Lu, Shu, R., and Zhu, Y., “Dysregulation and Dislocation of SFPQ Disturbed DNA Organization in Alzheimer's Disease and Frontotemporal Dementia.”, J Alzheimers Dis, vol. 61, no. 4, pp. 1311-1321, 2018.

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