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Cell Line
G. He, Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., Bettayeb, K., Flajolet, M., Gorelick, F., Wennogle, L. P., and Greengard, P., Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease., Nature, vol. 467, no. 7311, pp. 95-8, 2010.
S. A. Villeda, Plambeck, K. E., Middeldorp, J., Castellano, J. M., Mosher, K. I., Luo, J., Smith, L. K., Bieri, G., Lin, K., Berdnik, D., Wabl, R., Udeochu, J., Wheatley, E. G., Zou, B., Simmons, D. A., Xie, X. S., Longo, F. M., and Wyss-Coray, T., Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice., Nat Med, vol. 20, no. 6, pp. 659-63, 2014.
J. Geng, Xia, L., Li, W., Zhao, C., and Dou, F., Cycloheximide Treatment Causes a ZVAD-Sensitive Protease-Dependent Cleavage of Human Tau in Drosophila Cells., J Alzheimers Dis, vol. 49, no. 4, pp. 1161-8, 2016.
C. Stockburger, Miano, D., Baeumlisberger, M., Pallas, T., Arrey, T. N., Karas, M., Friedland, K., and Müller, W. E., A Mitochondrial Role of SV2a Protein in Aging and Alzheimer's Disease: Studies with Levetiracetam., J Alzheimers Dis, vol. 50, no. 1, pp. 201-15, 2016.
C. -cui Yang, Kuai, X. -xian, bin Gao, W. -, Yu, J. -chun, Wang, Q., Li, L., and Zhang, L., Morroniside-Induced PP2A Activation Antagonizes Tau Hyperphosphorylation in a Cellular Model of Neurodegeneration., J Alzheimers Dis, vol. 51, no. 1, pp. 33-44, 2016.
Y. Kim, Kim, C., Jang, H. Young, and Mook-Jung, I., Inhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation., J Alzheimers Dis, vol. 51, no. 4, pp. 1057-68, 2016.
R. Raha-Chowdhury, Henderson, J. W., Raha, A. Alexander, Stott, S. R. W., Vuono, R., Foscarin, S., Wilson, L., Annus, T., Fincham, R., Allinson, K., Devalia, V., Friedland, R. P., Holland, A., and Zaman, S. H., Erythromyeloid-Derived TREM2: A Major Determinant of Alzheimer's Disease Pathology in Down Syndrome., J Alzheimers Dis, vol. 61, no. 3, pp. 1143-1162, 2018.
K. Metsla, Kirss, S., Laks, K., Sildnik, G., Palgi, M., Palumaa, T., Tõugu, V., and Palumaa, P., α-Lipoic Acid Has the Potential to Normalize Copper Metabolism, Which Is Dysregulated in Alzheimer's Disease., J Alzheimers Dis, vol. 85, no. 2, pp. 715-728, 2022.
Cell Line, Tumor
A. Ezra, Rabinovich-Nikitin, I., Rabinovich-Toidman, P., and Solomon, B., Multifunctional Effect of Human Serum Albumin Reduces Alzheimer's Disease Related Pathologies in the 3xTg Mouse Model., J Alzheimers Dis, vol. 50, no. 1, pp. 175-88, 2016.
K. Bourgade, Le Page, A., Bocti, C., Witkowski, J. M., Dupuis, G., Frost, E. H., and Fülöp, T., Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model., J Alzheimers Dis, vol. 50, no. 4, pp. 1227-41, 2016.
M. Xie, Han, Y., Yu, Q., Wang, X., Wang, S., and Liao, X., UCH-L1 Inhibition Decreases the Microtubule-Binding Function of Tau Protein., J Alzheimers Dis, vol. 49, no. 2, pp. 353-63, 2016.
A. Maes, Anthonissen, R., Wambacq, S., Simons, K., and Verschaeve, L., The Cytome Assay as a Tool to Investigate the Possible Association Between Exposure to Extremely Low Frequency Magnetic Fields and an Increased Risk for Alzheimer's Disease., J Alzheimers Dis, vol. 50, no. 3, pp. 741-9, 2016.
M. Zhu, Huang, C., Ma, X., Wu, R., Zhu, W., Li, X., Liang, Z., Deng, F., Zhu, J., Xie, W., Yang, X., Jiang, Y., Wang, S., Wu, J., Geng, S., Xie, C., and Zhong, C., Modulation of miR-19 in Aluminum-Induced Neural Cell Apoptosis., J Alzheimers Dis, vol. 50, no. 4, pp. 1149-62, 2016.
T. Porter, Bharadwaj, P., Groth, D., Paxman, A., Laws, S. M., Martins, R. N., and Verdile, G., The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity., J Alzheimers Dis, vol. 50, no. 3, pp. 895-905, 2016.
A. K. Tripathi and Singh, N., Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease., J Alzheimers Dis, vol. 51, no. 1, pp. 107-21, 2016.
H. - H. Li, Lin, S. - L., Huang, C. - N., Lu, F. - J., Chiu, P. - Y., Huang, W. - N., Lai, T. - J., and Lin, C. - L., miR-302 Attenuates Amyloid-β-Induced Neurotoxicity through Activation of Akt Signaling., J Alzheimers Dis, vol. 50, no. 4, pp. 1083-98, 2016.
N. E. Gray, Zweig, J. A., Kawamoto, C., Quinn, J. F., and Copenhaver, P. F., STX, a Novel Membrane Estrogen Receptor Ligand, Protects Against Amyloid-β Toxicity., J Alzheimers Dis, vol. 51, no. 2, pp. 391-403, 2016.
A. Belkacemi and Ramassamy, C., Anthocyanins Protect SK-N-SH Cells Against Acrolein-Induced Toxicity by Preserving the Cellular Redox State., J Alzheimers Dis, vol. 50, no. 4, pp. 981-98, 2016.
S. Min Son, Shin, H. - J., Byun, J., Kook, S. Young, Moon, M., Chang, Y. Jin, and Mook-Jung, I., Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation., J Alzheimers Dis, vol. 51, no. 4, pp. 1197-208, 2016.
G. Marwarha, Rostad, S., Lilek, J., Kleinjan, M., Schommer, J., and Ghribi, O., Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation., J Alzheimers Dis, vol. 57, no. 3, pp. 907-925, 2017.
P. R. Manzine, Pelucchi, S., Horst, M. A., Vale, F. A. C., Pavarini, S. C. I., Audano, M., Mitro, N., Di Luca, M., Marcello, E., and Cominetti, M. R., microRNA 221 Targets ADAM10 mRNA and is Downregulated in Alzheimer's Disease., J Alzheimers Dis, vol. 61, no. 1, pp. 113-123, 2018.
J. Lu, Shu, R., and Zhu, Y., Dysregulation and Dislocation of SFPQ Disturbed DNA Organization in Alzheimer's Disease and Frontotemporal Dementia., J Alzheimers Dis, vol. 61, no. 4, pp. 1311-1321, 2018.