Current and Emerging Pharmacological Targets for the Treatment of Alzheimer’s Disease

See below for patents and applications: Paul C. Trippier, Nihar Kinarivala and Rose-Mary Boustany. ‘Functionalized pyridine carbamates with enhanced neuroprotective activity’. PCT Int. Appl. (2019), WO2019014547A8, 20190117. Vardan T. Karamyan, Paul C. Trippier, Thomas J. Abbruscato, David A. Ostrov, Srinidhi Jayaraman. ‘Enhancers of neurolysin activity’. PCT/US19/48702, 08/29/2019. Paul C. Trippier and Paul S. Brookes. ‘Method of treating cancer with Atpenin A5 derivatives’. U.S. Provisional Patent Appl. 62/670479, 05/11/2018. Paul C. Trippier, Kshitij Verma, Tianzhu Zang and Trevor Penning. ‘Highly selective AKR1C3 inhibitors and methods of use thereof’. PCT Int. Appl. (2018), WO2018148721 A1, 20180816. Paul C. Trippier and Paul Webb. ‘Novel phosphonate compounds as peroxisome proliferator-activated receptor β/δ agonists with neuroprotective activity’. U.S. Provisional Patent Appl. US 62/422797, 11/16/2016.