Identification of a cascade of changes in activities of daily living preceding short-term clinical deterioration in mild Alzheimer’s disease via lead-lag analysis

Manuscript Number: 

20-0230R2

Author(s): 
Chris Bauer, Lutz Frölich, Manuel Fuentes, Frank Jessen, Luca Kleineidam, Arne Klostermann, Stefan Klöppel, Johannes Kornhuber, Wolfgang Maier, Oliver Peters, Vera Schieting, Johannes Schuchhardt, Stefan J. Teipel, Michael Wagner, Jens Wiltfang

Disclosures

Chris Bauer

  • Nothing to Disclose

Lutz Frölich

  • Consulting Fees:
    Eli Lilly, Axon Neuroscience, Biogen, Boehringer Ingelheim, Eisai, Functional Neuromodulation, Lundbeck, MerckSharpe & Dohme, Pharnext, Roche, Schwabe Pharma
    Lecture Fees:
    Roche, Schwabe Pharma

Manuel Fuentes

  • Nothing to Disclose

Frank Jessen

  • Consulting Fees:
    Advisory fees from ESAI, Roche, Biogen, AC Immune, Janssen

Luca Kleineidam

  • Nothing to Disclose

Stefan Klöppel

  • Lecture Fees:
    Vifor Pharma. Chairing a lecture on depression in the elderly.

Arne Klostermann

  • Nothing to Disclose

Johannes Kornhuber

  • Nothing to Disclose

Wolfgang Maier

  • Nothing to Disclose

Oliver Peters

  • Consulting Fees:
    Biogen, Roche
    Lecture Fees:
    Roche
    Grants
    • Agency: 
      Biogen
      Dates: 
      2016-2020
    • Agency: 
      Roche
      Dates: 
      2017-2020
    • Agency: 
      Novartis
      Dates: 
      2017-2020
    • Agency: 
      Janssen
      Dates: 
      2017-2019
    • Agency: 
      Pharmatrophix
      Dates: 
      2017-2020

Vera Schieting

  • Nothing to Disclose

Johannes Schuchhardt

  • Nothing to Disclose

Stefan J. Teipel

  • Consulting Fees:
    Advisory Board memberships for Roche, Biogen
    Lecture Fees:
    2019, from Roche, presentation at DGN

Michael Wagner

  • Nothing to Disclose

Jens Wiltfang

  • Consulting Fees:
    Eli Lilly -Travel costs Hoffmann-La-Roche MSD Sharp + Dome Boehringer-Ingelheim Immungenetics Abbot EPD
    Lecture Fees:
    Med update GmbH twice a year Pfizer honorarium for lectures Janssen-Cilag honorarium for lectures Actelion
    Patents/Royalties
    Patent no.: EP1270592B1; patent no.: US 6,849,416 B2; patent no.: EP2095128B1; patent no.: EP3105589A1