Chiara Zoia, PhD in Morfological Sci-Neurosci-

JAD profile

Affiliation(s): 

School of Medicine and Surgery; Center of Neurosci.; University of Milano Bicocca; Italy

ORCID URL: 

http://orcid.org/0000-0003-1654-4996

Areas of Interest: 

neurobiology; biochemical and molecular markers; neurological diseases; Alzheimer's disease

Biography & Research: 

POSITION TITLE -Ph.D. Biologist, Manager of Neurobiology Laboratory, Center for Neuroscience, -Adjunct Prof. in Neurobiology and human peripheral model, Dept. of Surgery and Translational Medicine, Univ. of Study of Mialno-Bicocca EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as chemistry, and include postdoctoral training.) • 2001: PhD in Morphological science, Department of Anatomy, School of Medicine, University of Milano • 1999: Qualifying examination, School of Mathematics Physics and Natural Sciences, University of Milano • 1995: degree in Biological Science, Department of Pathology, School of Mathematics Physics and Natural Sciences, University of Milano RESEARCH AND PROFESSIONAL EXPERIENCE march '93 /december '95: neuropathology in in-vivo and in vitro experimental models (Lab. of Prof. Scalabrino, General Pathology Inst., School of Medicine, University of Milano. From January '96 she attends Lab. of Neurobiology, directed by Prof. Ferrarese, School of Medicine, D.N.T.B. Univ. of Study Milano-Bicocca and she develops studies of molecular biology, cellular cultures and neurochemistry about neurodegenerative (AD, PD and ALS) disorders. At the end of the 90s, she worked with Prof. J Rothstein (NIH, “J. Hopkins” University) for her studies about glutamate transporters. She collaborates with Prof. Tredici, Head of Dept., about morphological studies in C.N.S. and P.N.S. She also cooperated to research teams (IRCCS "E. Medea " of Bosisio Parini, Fondazione Pro Juventute "Don C. Gnocchi" of Milano and "M. Negri" Institute) about neurochemistry and neuroimmunology studies on epileptic, neuropsychiatric, Stroke and Multiple Scleroris patients. She joined in National project about Alzheimer’s disease, in collaboration with Pharmacology Inst. of Univ. of Milano (Prof. Cattabeni, Prof. Di Luca) and with different research teams of Italian Interdisciplinary Network in Alzheimer’s Disease (ITINAD). Currently Dr. Zoia is conducting studies on the molecular regulation of specific signal transduction pathways ( p38 stress -activated kinase , JNK and ERK kinase and PKBAKT), following treatment with oxidant and antioxidants substances, Abeta and glutamate cell growth and differentiation factors (ac. retinal and NGF) in ex vivo human and cellular models of neurodegenerative diseases (Alzheimer's and Parkinson's). She is involving in studies of the glutamatergic system settings in human peripheral models of Multiple Sclerosis, in collaboration with Dr. Gironi CAM Monza and IRCCS Don Gnocchi. She studies the glutamatergic system in ex vivo animal models of peripheral nervous system in basal conditions and multiple sclerosis (EAE), in collaboration with Prof. Dr. Cavaletti (Univ. Milano-Bicocca). She collaborates with Dr Perseghin (hematology department) and Dr. Villa (department of vascular surgery), Hospital S. Gerardo-Monza, to study the molecular pathways of platelet-gel: “molecular mechanisms and therapeutic efficacy in the treatment of ulcers skin”. Now, she is performing molecular and biochemical studies about glutamate excitotoxicity, amyloid-beta oligomers role and MAPKinase signaling pathway in ex vivo peripheral models and in in vitro CNS models to study physiophatology of Alzheimer’s disease. She is also studying these pathways and mechanisms in iPs-derived neurons to better characterize their involvement in neuronal plasticity. Since 2001 she is a member of European society of Neuroscience (FENS) and of Italian Society for Neuroscience. Since November 2015 she is a member on Editorial Board of Alzheimer’s & Parkinson's Disease Journal. Moreover, she is a peer-reviewer of Dove Medical Press journals for Clinical Interventions in Aging, International Journal of Nanomedicine, Nanotechnology, Science and Applications and Research and Reports in Biology. Oct. 2015- now: Expert manager of Neurobiology Laboratory, Full-time position; Milan Center for Neuroscience, School of Medicine, Univ. of Study of Milano-Bicocca. Oct. 2012-Sept. 2015: Manager of Neurobiology Laboratory, Full-time position; Center for Neuroscience (2014), Dept. of Surgery and Translational Medicine, School of Medicine, Univ. of Study of Milano-Bicocca. Feb. 2005-Sept. 2012 : Manager of Neurobiology Laboratory, Full-time position; Dept. of Neuroscience, School of Medicine, Univ. of Study of Milano-Bicocca. Nov. 2000- Jan. 2005: Post-Doc Fellows research, Laboratory of Neurobiology; Dept. of Neuroscience, School of Medicine, Univ. of Study of Milano-Bicocca. Joined in 2007 in the Directory of Experts Global Grant INGENIO, Lombardy Region - European Social Fund as a Consultant Professional and scientific tutor. TEACHING ACTIVITY • Assistant professor of “Board of Qualification in Extrapyramidal Diseases” Institute of Biomedical Science, School of Medicine, University of Milano, June 1998. • Assistant professor of Neurobiology course, School of Medicine, University of Milano/University of Milano-Bicocca (a.a. 1998-‘99) (a.a. 1999-2000)/(a.a. 2000-2001) (a.a. 2001-2002) (a.a. 2002-2003) (a.a. 2003-2004),… until now • Professor of Neurobiology and experimental models, School of Medicine, Degree in Medical Biotechnologies, (a.a. 2004-2005), University of Milano –Bicocca. • Tutor for medical doctors, resident in Neurology, biological and pharmacological students to develop studies in Neuroscience, University of Milano –Bicocca. • Visiting lecturer in Neurobiology/Neuroscience at School of Medicine, University of Milano-Bicocca (2015) FELLOWSHIPS/AWARDS 1990: Study Fellow a.a. 1989/90 (University of Milano). 1999: "DE VISART ‘94/’95" for advancing in neuro-psyco-phathological science (University of Milano). 2000: SINS for "giovani e brillanti neuroscienziati" (FENS Brighton, 24-29 June 2000). 2002: SINS for "giovani e brillanti neuroscienziati" (FENS di Parigi, 13-17 luglio 2002). 2002: SINFP for “ Neuroscience Research” (SINFP di Milano, 9-12 Luglio 2002) 2002: National Awards “Gino Galletti Foundation” for the best Residence or Doctorate thesis in neurodegenerative pathologies (University of Bologna). Title: “Morphological, functional and molecular characterization of glutamate transporters in neurodegenerative diseases”. Maximum score obtained (excellent). h index:16 documents:32 citations 725