Amalia Bruni, MD

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Effects of Multiple Genetic Loci on Age at Onset in Frontotemporal Dementia.
March 23, 2018
very very very interesting!!!
Effects of Multiple Genetic Loci on Age at Onset in Frontotemporal Dementia.
March 23, 2018
very very very interesting!!!
Early-Life Exposure to Lead (Pb) Alters the Expression of microRNA that Target Proteins Associated with Alzheimer's Disease.
April 3, 2017
As environmental impact can influence neurodegeneration. Good paper.
Staging Alzheimer's Disease Risk by Sequencing Brain Function and Structure, Cerebrospinal Fluid, and Cognition Biomarkers.
April 3, 2017
an usefull clinic tool for future!
Preliminary Study of Plasma Exosomal Tau as a Potential Biomarker for Chronic Traumatic Encephalopathy.
April 3, 2017
A very interesting model and prommissing results.
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.
March 10, 2016
This consensus paper for the first time recognized presymptomatic Alzheimer's disease as a clinical entity and standardized the...
Cognitive reserve in ageing and Alzheimer's disease.
March 10, 2016
This paper is a seminal work for the definition of both cognitive reserve and brain reserve and to understanding their role in...
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline.
March 9, 2016
In the paper the A673T mutation in the APP gene protects against Alzheimer's disease and the mutation may also slow the normal...
Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition.
March 9, 2016
This article is very important from the point of view of early diagnosis and application of primary and secondary prevention...
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
March 9, 2016
This important work provides the opportunity to better characterize new candidate genes associated with Alzheimer's disease...
Plasma phospholipids identify antecedent memory impairment in older adults.
March 9, 2016
This report is very intresting because, for the first time, blood-based biomarkers are assayed for detecting preclinical AD,...
An epigenetic blockade of cognitive functions in the neurodegenerating brain.
March 9, 2016
The study conducted by Graff et al., has aroused my strong interest from the time when the role of epigenetics is emerging...
REST and stress resistance in ageing and Alzheimer's disease.
March 9, 2016
The paper I selected deserves considerable interest because it addresses its full attention, not on neurodegenerative aspects,...
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers.
March 8, 2016
The authors developped  a few years ago a very interesting model describing the temporal evolution of AD biomarkers  in ...
Propagation of tau pathology in a model of early Alzheimer's disease.
March 8, 2016
Tha authors developped an  interesting animal model that allowed them to unravell the sequence of events from expression of...