Raul Loera, PhD
Primary tabs
JAD profile
Affiliation(s):
Karolinska Institutet
ORCID URL:
Areas of Interest:
adult hippocampal neurogenesis
Biography & Research:
I spent two years in my master’s degree working with fibroblast cell lines (3T3-L1 and F422A, as well as human fibroblast primary cultures), I specifically studied the inhibition of adipose differentiation in a 3T3 cell line in response to several capsaicin analogues and the relationship of this inhibition to the expression of the expression of TRPV channel families. For my Ph.D., I investigated the postnatal regulation of P2X receptors in myenteric neurons from guinea pigs, a work that resulted in my first author publication with my director Dr. Barajas-López. We encountered a new neuron specific expression of P2X receptors that was dependent on postnatal development. Additionally, during my Ph.D., I did a one year doctoral stay in Dr. Jan D. Huizinga´s laboratory in Canada, where I standardized single cell transcript analysis tools for pacemaker cells of the gastrointestinal tract.
In my postdoctoral research at Karolinska Institutet I researched the role of oxysterols in neural and astrocytic differentiation in relationship with Alzheimer´s Disease. My main interest is to unravel the mechanisms that govern neural differentiation in embryonic development and adult stages.
