Gourav Roy Choudhury, PhD.

JAD profile

Affiliation(s): 

Texas Biomedical Research Institute

Areas of Interest: 

neuroscience, CNS neurodegeneration, stroke, Parkinson's disease, adult neural stem cells

Biography & Research: 

During PhD my research was focussed on understanding the biphasic functional role of astrocytes in a post-ischemic brain. Using a transgenic mouse model we successfully demonstrated the important function of p38 MAPK in regulating reactive astrogliosis following ischemic injury. I was also interested in the metabolic adaptation of astrocytes in extreme stress like ischemia and how pharmacologically augmented astrocyte function can be used as neuroprotective strategy in various CNS disorders. As a postdoctoral scientist my current research is focussed on generating specific neural lineages from pluripotent stem cells and testing their efficacy in primate models of stroke and Parkinson's disease. I am also interested in understanding the process of neurogenesis in higher order primate brains following ischemic injury .