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H. Bea Kuiperij, Ph.D.
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Affiliation(s):
Radboud University Medical Center; Department of Neurology
ORCID URL:
Areas of Interest:
Alzheimer's disease, cerebrospinal fluid (CSF) biomarkers, molecular mechanisms of neurodegeneration, blood-brain barrier, cerebral amyloid angiopathy, Parkinson's diseas
Biography & Research:
H. Bea Kuiperij (Ph.D.) has a broad background in biochemical and molecular biological research, in particular in the field of molecular signal transduction. She obtained her Ph.D. in biochemistry in 2004 at the University of Utrecht (The Netherlands) on the thesis entitled “Novel cAMP targets in cell proliferation”. She proceeded her scientific career as postdoctoral researcher in the department of Experimental Neurology at the University Medical Centre Utrecht (The Netherlands), where she got acquainted with neuroscience, and subsequently at the department of Immunohematology and Blood Transfusion at Leiden University Medical Centre (The Netherlands). Since 2008, she is appointed as senior postdoctoral researcher (assistant professor since 2014) in the department of Neurology at the Radboud University Medical Center (The Netherlands), in the neurochemistry research group of dr. Marcel M. Verbeek. In this position, dr. Kuiperij supervises Ph.D.-students (currently five; three completed previously) and research technicians. Since then, she is, and has been, involved in a variety of projects focused on development of diagnostic assays and identification of new biomarkers in biological fluids (cerebrospinal fluid, blood) for several neurodegenerative diseases (e.g. Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease, amyotrophic lateral sclerosis); and basic research projects on clearance mechanisms of the amyloid- β peptide across the blood-brain barrier.