Biography & Research:
Judith Miklossy has received her MD, PhD degrees and Board certificates of specialization in neurology, then in psychiatry and psychotherapy, with EU and AELE conform certificates from the Faculty of Medicine of the University of Debrecen, and the National Board of specialization in neurology and psychiatry in Hungary. She has received the university degree of PD or DSc and the Board certificate of specialization in neuropathology at the University of Lausanne and Swiss Medical Federation (FMH), in Switzerland. She was head of the Neurodegeneration research group at the University Institute of Pathology (CHUV, Lausanne), Switzerland, for over ten years. She has done molecular biology research and participated in the introduction of Alzheimer’s research in Temple University, Philadelphia, USA. She headed the neuropathology division of Kinsmen Laboratory of Neurological Research, in The University of British Columbia, Vancouver, Canada. She is on the board of directors or scientific advisory board of several international organizations or foundations. She is founder of the Alzheimer's Prevention International Foundation and presently Director of the foundation and the International Alzheimer Research Center in Switzerland.
She is actively involved in research on chronic inflammatory disorders, including Alzheimer's disease and Lyme disease. From 1993-1995 we have suggested that bacterial amyloid and DNA might contribute to amyloid deposition in AD and senile plaques correspond to colonies of spirochetes. A statistically significant association between spirochetes and AD fulfilled Hill’s criteria in favor of a causal relationship.
We have also reported the presence of local infection and inflammation in affected pancreatic islets in type-2 diabetes. Bacterial peptidoglycan, LPS and several bacteria, including spirochetes, Chlamydia pneumoniae and Helicobacter pylori were found to be associated with amyloid deposits in the affected Langerhans islets.
We reported that the major late or chronic forms of neurosyphilis were pathologically confirmed in Lyme disease and contributed to show evidence on the direct involvement of Borrelia burgdorferi in chronic Lyme neuroborreliosis.
We have shown that Borrelia burgdorferi cultivated from the brains of patients with chronic Lyme neuroborreliosis are virulent and invade neurons and glial cells and cause apoptosis.