Jacopo C. DiFrancesco, MD, PhD, Neurologist

JAD profile

Affiliation(s): 

Neurology Unit; San Gerardo Hospital; University of Milano-Bicocca; Monza; Italy; Neurophysiology and Diagnostic Epilepsy; Besta's Institute; Milano; Italy

ORCID URL: 

https://orcid.org/0000-0002-4102-1188

Areas of Interest: 

Cerebral Amyloid Angiopathy (CAA); Cerebral Amyloid Angiopathy-related inflammation (CAA-ri); Epilepsy; Genetic of epilepsy; HCN-channelopathies

Biography & Research: 

ACADEMIC ACHIEVEMENTS -RESIDENCY IN NEUROLOGY, University of Milano-Bicocca, Monza, Italy -PhD in NEUROSCIENCE, University of Milano-Bicocca, Monza, Italy -DEGREE in MEDICINE, University of Milano-Bicocca, Monza, Italy MAIN RESEARCH ACTIVITIES -Genetic of epilepsy: described and characterized the first HCN channels mutation (E515K on HCN2) in humans (DiFrancesco et al., 2011 J Neurosci) -Neurodegenerative disorders: demonstrated that the pathogenesis of a rare autoimmune encephalitis (CAA-ri) is mediated by specific anti amyloid-beta autoantibodies (DiFrancesco et al., 2011 Neurology; Piazza et al., 2013 Ann Neurol; Boncoraglio et al, 2014 J Alzheimers Dis) PREVIOUS POSITIONS -Research Fellow, Dept. of Neuroscience and Biomedical Technologies (DNTB), Univ. Milano-Bicocca, Italy -Visiting Researcher, Dept. Clinical Neurosciences, Univ. College Medical School (UCL), London, UK CURRENT POSITIONS -Clinical activity, Dept of Neurology and Stroke Unit, S. Gerardo Hospital, University Milano-Bicocca, Monza -Clinical researcher, Dept of Neurophysiology and Diagnostic Epileptology, Neurological Institute C. Besta, Milano -Research activity, Lab of Neurobiology, Milan Center for Neurosciences, University Milano-Bicocca, Monza -Regional Centre of Epilepsy and Operative Unit of Neurophysiology, S. Gerardo Hospital, Monza -Consultant Neurologist, Lab. of Molecular Physiology and Neurophysiology (The PaceLab), Dept. of Biosciences, University of Milano, Italy