Dr. Ruchi Jakhmola Mani, PhD
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Affiliation(s):
Proteomics and Translational Research Laboratory; Amity University Noida
ORCID URL:
Areas of Interest:
Alzheimer's Disease; Brain Diabetes, Type 3 Diabetes; Type 2 Diabetes, Parkinson's disease
Biography & Research:
Dr. Ruchi Jakhmola Mani is a neuroscientist and an academician with over 14 years of expertise in conducting preclinical studies, specializing in disease modeling within the fields of Neurology, Oncology, and Diabetes. She has several patents (granted and published), copyrights and an impressive track record of publications in prestigious journals such as Nature, Elsevier, Bentham Sciences, Taylor and Francis, Springer, and IntechOpen etc. She has conducted several programs on Alzheimer's Awareness. She is currently exploring amalgamation of machine learning and artificial intelligence to bring new insights in this area. Currently she is exploring role of nutrition in AD treatment. Some of her research work is as follows:
1. Jakhmola Mani, Ruchi, Nitu Dogra, and Deepshikha Pande Katare. "The Connection between Chronic Liver Damage and Sporadic Alzheimer’s Disease: Evidence and Insights from a Rat Model." Brain Sciences 13.10 (2023): 1391.
2. Jakhmola-Mani, Ruchi, Anam Islam, and Deepshikha P. Katare. "Liver-brain axis in sporadic Alzheimer’s disease: role of ten signature genes in a mouse model." CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders) 20.9 (2021): 871-885.
3. Mittal, Khyati, Ruchi Jakhmola Mani, and Deepshikha Pande Katare. "Type 3 diabetes: cross talk between differentially regulated proteins of type 2 diabetes mellitus and Alzheimer’s disease." Scientific reports 6.1 (2016): 25589.
4. Dogra, Nitu, Ruchi Jakhmola Mani, and Deepshikha Pande Katare. "The gut-brain axis: Two ways signaling in Parkinson’s disease." Cellular and Molecular Neurobiology (2022): 1-18.
5. Agarwal, Kritie, Deepshikha Pande Katare, and Ruchi Jakhmola-Mani. "Foresee novel targets for Alzheimer’s disease by investigating repurposed drugs." CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders) (2023).
6. Sharma, Mukund, Deepshikha Pande Katare, Ritu Chauhan, Shikha Rani, and Ruchi Jakhmola Mani. "Artificial intelligence: the future of neuroscience." Artificial Intelligence and Computational Dynamics for Biomedical Research 8 (2022): 97.
7. Jakhmola-Mani, Ruchi, Khyati Mittal, and Deepshikha Pande Katare. "Alarm Test: A Novel Chemical-Free Behavioural Assessment Tool for Zebrafish." Zebrafish in Biomedical Research. IntechOpen, 2020.
8. Mani, Ruchi Jakhmola, et al. "A Systematic Review of Molecular Pathway Analysis of Drugs for Potential Use in Liver Cancer Treatment." Drugs and Drug Candidates 2.2 (2023): 210-231.
9. Mani, Ruchi Jakhmola, et al. "In Silico Approach to Evaluate the Efficacy of Dietary Flavonoids and Their Role in Alzheimer's Disease." International Journal of Pharmaceutical Sciences Review an d Research 34 (2015): 94-102.
10. Jakhmola Mani, Ruchi, et al. "Deciphering underlying mechanism of Sars-CoV-2 infection in humans and revealing the therapeutic potential of bioactive constituents from Nigella sativa to combat COVID19: in-silico study." Journal of Biomolecular Structure and Dynamics 40.6 (2022): 2417-2429.
